Abstract
Subsequent to our study of the dosimetry of radiopharmaceuticals for adrenal cortex imaging (1) we have performed whole body biokinetic and retention measurements with I131-MIBG in animals and man. Biokinetic data from mice were utilized to replace unmeasurable organ kinetics in human. In man we recorded whole body profiles from which only liver and thyroid accumulation could be evaluated together with the distribution and excretion of the radiopharmaceutical in the whole body.
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References
Deckart H, Ertl S, Blottner A, Tautz M, Weiss ML, Retention und Strahlenbelastung nach intravenöser Injektion von ScintadrenR. In: Radioaktive Isotope in Klinik und Forschung. Höfer R, Bergmann H, (eds), Egermann H, Wien, Vol. 16/2, pp 663–680, 1984.
Swanson DP, Carey JE, Brown LE, Kline RC, Wieland DM, Thrall JH, Beierwaltes WH, Human absorbed dose calculations for Iodine-131 and Iodine-123 labeled meta-iodobenzyl-guanidine (mIBG): A potential myocardial and adrenal medullary imaging agent. 3rd Int. Radiopharm. Dosimetry Symp., HHS Publication, FDA 81-8166, pp 213–224, 1981.
Kimmig B, Bubeck B, Eisenhut M, Lange D, Die Strahlenbelastung bei der diagnostischen und therapeutischen Anwendung von 131J-meta-Benzylguanidin (MIBG). NucCompact 14:353, 1983.
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© 1986 Martinus Nijhoff Publishers, Dordrecht
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Deckart, H., Ertl, S., Blottner, A., Weiss, M., Tautz, M. (1986). Incorporation Dosimetry of I131-Meta-Iodobenzylguanidine (131I-MIBG). In: Cox, P.H., Mather, S.J., Sampson, C.B., Lazarus, C.R. (eds) Progress in Radiopharmacy. Developments in Nuclear Medicine, vol 10. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4297-4_25
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DOI: https://doi.org/10.1007/978-94-009-4297-4_25
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-8410-9
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