Abstract
Monoclonal antibodies (McAbs) to Infectious Bronchitis Virus (IBV) were prepared and tested for reactivity to different IBV variant strains by an indirect enzyme-immunoassay.
With the exception of two McAbs specific for the nucleoprotein, which did not recognize the SE-17 strain, all McAbs to the matrix and nucleoprotein reacted with all strains tested. McAbs to the matrix and nucleoprotein, therefore, are suitable for diagnostic purposes.
On basis of the reactivity pattern to variant strains of a panel of McAbs specific for the peplomer protein, it was possible to differentiate Dutch variant strains into three groups.
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© 1986 ECSC, EEC, EAEC, Brussels-Luxembourg
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Koch, G., Hartog, L., Kant, A., van Roozelaar, D., de Boer, G.F. (1986). Antigenic Differentiation of Avian Bronchitis Virus Variant Strains Employing Monoclonal Antibodies. In: McFerran, J.B., McNulty, M.S. (eds) Acute Virus Infections of Poultry. Current Topics in Veterinary Medicine and Animal Science, vol 37. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4287-5_13
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