Summary
Advances based upon the detector elements instead of X-ray film have greatly increased the power of X-ray imaging. Computed tomography (CT) creates cross-sectional rather than projected images. Recently, high speed CT devices have been developed for cardiovascular studies. The Cine-CT scanner employs a scanning electron beam deflected on an extended tungsten target ring. Fast scans of 50 millisecond exposures at multiple levels can provide information concerning blood flow in vessels and tissues, myocardial wall motion, valve integrity, coronary bypass graft patency and proximal coronary artery anatomy. Cine-CT dynamic scanning can also provide volume imaging with small quantities (0.05–1.5 ml/kg) of contrast medium administered via peripheral vein injections.
Cine-CT provides simultaneous measurements of cardic dimentions and function and is rapidly becoming a new tool for quantitating myocardial blood flow, cardiac chamber volumes and wall mechanics. The future outlook is very promising fo this three-dimensional cine-CT technique with high spatial resolution. High speed CT should provide unique diagnostic information and as technology continues to improve at a rapid speed, this new imaging modality could be a challenge for angiography.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Lipton MJ, Higgins CB: Evaluation of ischemic heart disease by computerized transmission tomography. Radiology Clinics of North America 18, 1980: 557–576.
Moncada R, Baker M, Salinas M, Demos TC, Churchill R, Love L, Reynes C, Hale D, Cardosso M, Pifarre R, Gunnar RM: Diagnostic role of computed tomography in pericardial heart disease: Congenital defects, thickening, neoplasms, and effusions. Am Heart J 103, 1982: 263–282.
Higgins CB, Carlsson E, Lipton MJ: CT of the heart and the great vessels: Experimental evaluation and clinical application. Futura Publishing Co., Mount Kisco, New York, 1983.
Lackner K, Thurn P: Computed tomography of the heart. ECG-gated and continuous scans. Radiology 140, 1981: 413–420.
Doppman JL, Rienmuller R, Lissner J, Cyran J, Bolte H-D, Strauer BE, Hellwig H: Computed tomography in constrictive pericardial disease. J Computed Assisted Tomography 5, 1981: 5–11.
Bohn J, Reinmiiller R, Seiderer M, Strauer BE: The non-invasive determination of the end- diastolic volume of the left ventricle: a comparison of cineangiographic, two-dimensional echocardiographic, multiple gated angiographic and computertomographic techniques. Z Kardiol 72, 1983: 438–447.
Masuda Y, Yoshida H, Morooka N, Takahashi O, Watanobe S, Inagaki Y, Uchiyama G, Tateno Y: ECG synchronized computed tomography in clinical evaluation of total and regional cardiac motion: Comparison of postmyocardial infarction to normal hearts by rapid sequential imaging. Am Heart J 103, 1982: 230–238.
Godwin JD, Hefkins RL, Skiöldebrand CG, Federle MP, Upton MJ: Evaluation of dissections and aneurysms of the thoracic aorta by conventional and dynamic CT scanning. Radiology 136, 1980: 125–133.
Tomoda H, Hoshiai M, Furuya H, Shotsu A, Ootaki M, Matsuyama S: Evaluation of left ventricular thrombus with computed tomography. Am J Cardiol 48, 1981: 573–577.
Reinmüller R, Ontyd J, Krappel W, Strauer B-E: Infarktbedingte Veränderungen des links- ventrikulären Myokards in der kardialen Computertomographie. Fortsch Röntgenstr 138, 1983: 403–411.
Ritman EL, Robb RA, Johnson SA, Chevalier PA, Gilbert BK, Greenleaf JF, Sturm RE, Wood EH: Quantitative imaging of the structure and function of the heart, lungs and circulation. Mayo Clinic Proc 53, 1978: 3–11.
Boyd DP, Gould RG, Quinn JR, Sparks R: A proposed dynamic cardiac 3-D densitometer for early detection and evaluation of heart disease. IEEE Trans Nucl Sei 26, 1979: 2724–2727.
Boyd DP: Future technologies, transmission CT in radiology of the skull and brain: technical aspects of computed tomography.. TH Newton and DG Polk (Eds.), St. Louis, MO. CV Mosby, 1981: chapter 13.
Boyd DP, Lipton MJ: Cardiac computed tomography. Proc IEEE 71, 1983: 298–307.
Peschmann KR, Couch JL, Parker DL: New developments in digital X-ray detection. In: Digital Radiography, SPIE Proceedings 314, 1981: 5054.
Lipton MJ, Hayashi TT, Boyd D, Carlsson E: Measurement of left ventricular cast volume by computed tomography. Radiology 127, 1978: 419–423.
Lipton MJ, Hayashi TT, Davis PL, Carlsson E: The effects of orientation on volume measurements of human left ventricular casts. Invest Radiol 15, 1980: 469–474.
Ringerts HG, Rodgers B, Lipton MJ, Cann C, Carlsson E: Assessment of human right ventricular cast volume by CT and angiocardiography. Invest Radiol 20, 1985: 29–32.
Skiöldebrand CG, Ovenfors C-O, Mavroudis C, Lipton MJ: Assessment of ventricular wall thickness in vivo by computed transmission tomography. Circulation 61, 1980: 960–965.
Skiöldebrand CG, Lipton MJ, Mavroudis C, Hayashi TT: Determination of left ventricular mass by computed tomography. Am J Cardiol 49, 1982: 63–70.
Teicholz LE, Kreule T, Herman MV, Gorlin R: Problems in echocardiographic volume determinations: Echocardiographic- angiographic correlations in the presence or absence of asynergy. Am J Cardiol 37, 1976: 7–11.
Schiller NB, Skiöldebrand CG, Schiller EJ, Mavroudis CC, Silverman NH, Rahimtoola SM, Lipton MJ: Canine left ventricular mass estimation by two-dimensional echocardiography. Circulation 68, 1983: 210–216.
Peck WW, Maruini GBJ, Slutsky RA, Mattrey RF, Higgins CB: In vivo assessment by computed tomography of the natural progression of infarct size, left ventricular muscle mass and function after acute myocardial infarction in the dog. Am J Cardiol 53, 1984: 929–935.
Iwasaki T, Sinak LJ, Hoffman EA, Robb RA, Harris LD, Bahn RC, Ritman EL: Mass of left ventricular myocardium estimated with dynamic spatial reconstructor. Am J Physiol 246, 1984: H138–H142.
Feiring AJ, Rumberger JA, Reiter SJ, Skorton DJ, Collins SM, Lipton MJ, Higgins CB, Ell S, Marcus ML: Determination of left ventricular mass in dogs with rapid-acquisition cardiac Computed tomographic scanning. Circulation 72, 1985: 1355–1364.
Adams DF, Hessel SJ, Judy PF, Stein JA, Abrams HL: Computed tomography of the normal and infarcted myocardium. Am J Roentgenol 126, 1976: 786–791.
Doherty PW, Lipton MJ, Berninger WH, Skiöldebrand CG, Carlsson E, Redington RW: Detection and quantitation of myocardial infarction in vivo using transmission computed tomography. Circulation 63, 1981: 597–606.
Slutsky RA, Mattrey RF, Long SA, Higgins CB: In vivo estimation of myocardial infarct size and left ventricular function by prospectively gated computerized transmission tomography. Circulation 67, 1983: 759–765.
Kramer PH, Goldstein JA, Herfkens RJ, Lipton MJ, Brundage BH: Imaging of acute myocardial infarction in man with contrast-enhanced transmission tomography. Am Heart J 108, 1984: 1514–1523.
Kramer PH, Goldstein JA, Herfkens RJ, Lipton MJ, Brundage BH: Imaging of acute myocardial infarction in man with contrast-enhanced transmission tomography. Am Heart J 108, 1984: 1514–1523.
Goldstein JA, Schiller NB, Lipton MJ, Ports TA, Brundage BH: Evaluation of left ventricular thrombi by contrast-enhanced computed tomography and two-dimensional echocardiography. Am J Cardiol 57, 1986: 757–760.
Farmer D, Lipton MJ, Higgins CB, Ringertz H, Dean PB, Sievers R, Boyd DP: In vivo assessment of left ventricular wall and chamber dynamics during transient myocardial ischemia using cine computed tomography. Am J Cardiol 55, 1985: 560–565.
Farmer D, Lipton MJ, Higgins CB, Ringertz H, Dean PB, Sievers R, Boyd DP: In vivo assessment of left ventricular wall and chamber dynamics during transient myocardial ischemia using cine computed tomography. Am J Cardiol 55, 1985: 560–565.
Brundage BH, Lipton MJ, Hefkens RJ, Berninger WH, Redington RW, Chatterjee K, Carlsson E: Detection of patent coronary bypass grafts by computed tomography: A preliminary report. Circulation 61, 1980: 826–831.
Brundage BH, Lipton MJ, Hefkens RJ, Berninger WH, Redington RW, Chatterjee K, Carlsson E: Detection of patent coronary bypass grafts by computed tomography: A preliminary report. Circulation 61, 1980: 826–831.
Jaschke W, Gould R, Assimakopoulos PA, et al: Flow measurements with a high speed CT scanner. Invest Radiol, 1985: submitted.
Sapirstein LA: Regional blood flow by fractional distribution of indicators. Am J Physiol 193, 1958: 161–168.
Zierler KL: Equations for measuring blood flow by external monitoring of radioisotopes. Circ Res 16, 1965: 309–321.
Thompson HK, Starmer CF, Whalen RE, Mcintosh HD: Indicator transit time considered as a gamma variate. Circ Res 14, 1964: 502–515.
Nassi M, Brody WR: Regional myocardial flow estimation using computed tomography. Med Phys 8, 1981: 302–307.
Klingensmith III WC: Regional blood flow with first circulation time-indicator curves: A simplified, physiologic method of interpretation. Radiology 149, 1983: 281–286.
Lipton MJ, Dean PB, Farmer D, Ringertz HG, Higgins CB: Measurement of regional myocardial blood by cine computed tomography. Circulation 70, 1984: 11–169. (Abstract)
Mullani NA, Gould KL: First-pass measurements of regional blood flow with external detectors. J Nucl Med 24, 1983: 577–581.
Rumberger J A, Fiering AJ, Lipton MJ, Higgins CB, Marcus ML: Measurement of myocardial perfusion by ultrafast CT. JACC 5, 1985: 500. (Abstract)
Doherty PW, Skiöldebrand CG, Redington RW, Berninger WH, Lipton MJ: Measurement of regional changes in myocardial perfusion using dynamic computed tomography and contrast medium. Acta Radiol Diagn 24, 1984: 297–303.
Jaschke W, Cogan MG, Sievers R, Gould R, Lipton MJ: Measurement of renal blood flow by cine computed tomography. Submitted, Kidney International, 1985.
Doppman JL, Reinmuller R, Lissner J, Cyran J, Bolte HD, Straver BE, Hellwig H: Computed tomography in constrictive pericardial disease. Journal of Computed Assisted Tomography 5, 1981: 1–11.
Moncada R, Salinas M, Churchill R, Love L, Reynes C, Demos TC, Hale D, Schreiber R: Patency of saphenous aortocoronary-bypass grafts demonstrated by computed tomography. New Engl J Med 303, 1980: 503–505.
Lipton MJ, Higgins CB: Computed tomography: The technique and its use for the evaluation of cardiocirculatory anatomy and function. In: Pediatric Cardiac Imaging. WF Friedman, CB Higgins (Eds), Saunders Publishers, Philadelphia, 1984: 120–134.
Fisher M, Lipton MJ, Higgins CB: Magnetic resonance imaging and computed tomography in congenital heart disease. Sem. Roentgen. 20, 1985: 272–282.
Lipton MJ, Higgins CB, Farmer D, Boyd DP: Cardiac imaging with a high speed Cine-CT scanner. Preliminary results. Radiology 152, 1984: 579–582.
Lipton MJ, Herfkens RJ: Computed tomography of the heart and pericardium. In: CT of the Body. A Moss, G Gamsu, H Genant (Eds.), WB Saunders, Co., Philadelphia, PA, 1983: 401–425.
Inagaki Y, Masuda Y: Diagnosis of cardiovascular disease by CT. Igaku-Shion Ltd, Tokyo, Japan, 1983.
Farmer DW, Lipton MJ, Webb WR, Ringertz H, Higgins CB: Computed tomography in congenital heart disease. J Comp Assist Tomogr 8, 1984: 677–687.
Farmer DW, Lipton MJ, Webb WR, Ringertz H, Higgins CB: Computed tomography in congenital heart disease. J Comp Assist Tomogr 8, 1984: 677–687.
Lanzer P, Garrett J, Sievers R, Gould R, Botvinick E, Lipton M, Higgins C: Wall thickening dynamics; assessment by Cine computed tomography. Circulation 72 (Supp III), 1985: III - 180 (Abstract).
Garrett JS, Jaschke W, Aherne T, Higgins CB, Lipton MJ: Quantitation of intracardiac shunts by Cine-CT. Circulation 72 (Supp III), 1985: 111–27 (Abstract).
Brasch RC, Boyd DP, Gooding CA: Computed tomography scanning in children: comparison of radiation dose and resolving power of commercial CT scanners. Am J Roentgenol 131, 1978: 95–101.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Martinus Nijhoff Publishers
About this chapter
Cite this chapter
Lipton, M.J. (1986). CT of the heart. In: Reiber, J.H.C., Serruys, P.W. (eds) State of the Art in Quantitative Coronary Arteriography. Developments in Cardiovascular Medicine, vol 53. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4279-0_6
Download citation
DOI: https://doi.org/10.1007/978-94-009-4279-0_6
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-8401-7
Online ISBN: 978-94-009-4279-0
eBook Packages: Springer Book Archive