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Problems and Prospect of Histoincompatible Bone Marrow Transplantation Studied in Rhesus Monkeys

  • G. Wagemaker
Part of the Developments in Oncology book series (DION, volume 45)

Abstract

Allogeneic bone marrow transplantation is a demonstrated effective therapy for a variety of congenital and acquired diseases of the lympho-hemopoietic system (1). Nevertheless, the possible immunological complications, which are graft rejection and graft-versus-host disease (GvHD), result in risks that counterbalance for many diseases the possible benefit for the patients, even if an HLA-identical family donor is available. For this reason, bone marrow transplantation is as yet restricted to diseases with a poor prognosis if treated otherwise.

Keywords

Bone Marrow Transplantation Rhesus Monkey Median Survival Time Acute GvHD Hemopoietic Stem Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Martinus Nijhoff Publishers, Dordrecht 1986

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  • G. Wagemaker

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