Application of Information Processing Techniques to Ophthalmic Imaging



A digital fundus imaging system, based on a conventional fundus camera, and employing a charge-coupled device array is presented. The processing steps required to convert images formed from monochromatic light reflected from the back of the eye into quantitative maps of spectral reflectance are discussed. Three examples of the potential of spectral reflectance images to characterize patho-physiological processes are examined in the context of the early diagnosis of diabetic retinopathy, choroidal melanoma, and glaucoma respectively. Preliminary studies on the utility of shape analysis by invariant moments for characterization of the optic nerve in glaucoma, and texture analysis by the spatial gray-level dependency method for characterization of pigmented lesions are described. Finally, a new and simple technique for measurement of three-dimensional optic nerve topography is presented which promises to be much more accurate than existing photogrammetric or optical sectioning methods. Results of this technique on larger objects than the eye are shown and an error analysis for the optic nerve is derived.


Optic Nerve Optic Nerve Head Spectral Reflectance Information Processing Technique Invariant Moment 
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Copyright information

© Martinus Nijhoff Publishers, Dordrecht 1986

Authors and Affiliations

  1. 1.North Shore University Hospital/Cornell UniversityManhassetUSA
  2. 2.New York Institute of TechnologyCenter for Optics, Lasers and Holography and NYCOMOld WestburyUSA

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