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The Maturation of the Control of Respiration in Infancy

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Abstract

During fetal life the control of gas exchange by the placenta is largely under maternal control1. The fetus responds to fluctuations in supply or demand of oxygen by chemoreflex modulation of regional blood flow1. The fetus thus makes active responses to fluctuations in blood gas tensions, but they are mediated almost entirely by cardiovascular adaptations. In contrast the adult responds to alterations of blood gas tensions by mechanisms which are almost entirely respiratory.

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Abbreviations

\(\dot VE\) :

Minute ventilation.

QS:

Quiet sleep.

REM:

Rapid eye movement sleep.

\(\dot Q\) :

Cardiac output.

T :

Transit time from lung to carotid body.

VA:

Volume of the lung compartment.

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Fleming, P.J., Levine, M.R., Long, A.M., Cleave, J. (1987). The Maturation of the Control of Respiration in Infancy. In: Walters, D.V., Strang, L.B., Geubelle, F. (eds) Physiology of the Fetal and Neonatal Lung. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4155-7_8

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  • DOI: https://doi.org/10.1007/978-94-009-4155-7_8

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-8344-7

  • Online ISBN: 978-94-009-4155-7

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