Overview
The studies discussed here concern general mechanisms of lung liquid and solute absorption in the immediate perinatal period, as well as specific characteristics of these phenomena in premature surfactant-deficient lambs. Descriptions of lung liquid and solute absorption are developed for such lambs, and correlated with experiments where the surfactant deficiency is ameliorated by instillation of an exogenous surfactant preparation prior to the start of ventilation. Of particular interest is the absorption of fetal lung liquid volume, surfactant phospholipid, and radiolabeled alveolar solutes of known radius (albumin, cytochrome C and cyanocobalamin), together with the transport of unlabelled proteins into alveoli during the first 90 min of ventilation.
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References
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Egan, E.A., Kwong, M.S., Notter, R.H. (1987). Absorption of Fetal Lung Liquid and Exogenous Surfactant in Premature Lambs. In: Walters, D.V., Strang, L.B., Geubelle, F. (eds) Physiology of the Fetal and Neonatal Lung. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4155-7_15
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DOI: https://doi.org/10.1007/978-94-009-4155-7_15
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