Abstract
Isolated hepatocytes transplanted into the spleen of rats proliferate. 6 – 24 months after transplantation a morphological structure can be observed comparable to that of a normal liver. Only little is known on the functions of the ectopic liver in the spleen (1, 3). We therefore have investigated the activities of liver enzymes of different metabolic functions and intracellular localisation in the hepatized spleens.
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References
Mito, M., Ebata, H., Kusano, M., Onishi, T., Saito, T Sakamoto, S., (1979). Morphology and function of isolated hepatocytes transplanted into rat spleen. Transplantation 28, 499–505
Mito, M., Ebata, H., Kusano, M., Onishi, T., Nozawa, M., (1981). Is potal venous blood essential for liver cell growth and proliferation? Eur.Surg.Res. 13 57–58
Lösgen, H., Vonnahme, F.J., Stauch, D., Ohlendorf, S. Schmidt, E., Brunner, G., (1984). Autologe Transplantation isolierter Leberzellen in die Milz bei der Ratte In: Zelder, O. et al. (eds). Experimentelle und klinische Hepatologie IV; Schattauer, Stuttgart, pp 259–264
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© 1986 MTP Press Limited
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Lösgen, H., Yamamoto, T., Kusano, T., Schmidt, E., Mito, M., Brunner, G. (1986). Functional Assessment of Hepatocytes after Syngeneic Transplantation into Rat Spleen. In: Brölsch, C.E., Zelder, O. (eds) Experimental and Clinical Hepatology. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4151-9_21
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DOI: https://doi.org/10.1007/978-94-009-4151-9_21
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-8342-3
Online ISBN: 978-94-009-4151-9
eBook Packages: Springer Book Archive