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Abstract

The function of DNA is to carry the genetic message from generation to generation, and to allow the expression of that message under appropriate conditions. DNA molecules are very large and carry the information for the synthesis of many proteins, not all of which are required at the same time. Problems will obviously arise when it comes to packaging such long lengths of DNA into a cell in such a way as to allow programmed access to the encoded information. These problems are compounded by the fact that the DNA duplex must replicate and the two daughter DNA molecules must segregate to the two daughter cells. In this chapter we shall look at the structures involved in these processes. These structures are called chromosomes and consist not only of the DNA but of a variety of associated proteins.

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Adams, R.L.P., Knowler, J.T., Leader, D.P. (1986). Chromosome organization. In: The Biochemistry of the Nucleic Acids. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-4103-8_3

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