Abstract
We have previously shown that unstimulated peripheral blood mononuclear cells (PBMC) produce an interferon— (IFN)— like substance when treated with compounds capable of inhibiting transcription, such as actinomycin D, diribofuranosylbenzimidazole, and alpha amanitine (1–3). Since the production did not occur in the presence of inhibitors of protein synthesis, it was inferred that the IFN—like substance was a newly synthesized protein whose mRNA was preformed in at least some of the cells (2).
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© 1987 Martinus Nijhoff Publishers, Dordrecht
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Dianzani, F., Dolei, A., Gentile, M. (1987). A New Type of Interferon-Like Protein Produced by Peripheral Blood Mononuclear Cells Treated with Inhibitors of Transcription. In: Cantell, K., Schellekens, H. (eds) The Biology of the Interferon System 1986. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3543-3_6
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DOI: https://doi.org/10.1007/978-94-009-3543-3_6
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