Pre- and Perinatal Factors and Neurological Dysfunction

  • Hendrik J. Huisjes
Part of the Topics in the Neurosciences book series (TNSC, volume 6)


In the majority of cases, serious motor handicap and developmental retardation have their origin in the prae- and perinatal period (Hagberg, 1975; Holm, 1982). Among 3162 consecutive singleton births which took place in our hospital in 1975–1978, 260 were found to result in neurologically abnormal infants (Table 1). Fourteen of these appeared to be handicapped when examined at 4–7 years of age. Among a control group of 160 neurologically normal newborns, matched for date of birth, none were neurologically abnormal at follow-up. Children with minor neurological dysfunction occurred in both groups, but the number was three times as large in the neonatally abnormal group (Table 2).


Cerebral Palsy Preterm Birth Neurological Dysfunction Perinatal Period Newborn Period 
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© Martinus Nijhoff Publishers, Dordrecht. 1987

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  • Hendrik J. Huisjes

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