Parasympathetic effects on electrophysiological properties of mammalian ventricular tissues

  • John C. Bailey
  • Eric N. Prystowsky
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 71)


The heart is regulated by both limbs of the autonomic nervous system. In the sinoatrial node, the parasympathetic nervous system predominates over the sympathetic nervous system in control of heart rate (Jose and Taylor, 1969; Levy and Zieske, 1969; Prystowsky et al. 1981). In animals and human AV nodal function is under balanced influence of the parasympathetic and sympathetic nervous systems (Levy and Zieske, 1969; Prystowsky et al. 1981). The importance of resting parasympathetic tone on human ventricular refractoriness has only recently been postulated (see Reviews by Higgins, et al. 1973; Zipes et al. 1981; Rardon and Bailey, 1983).


Action Potential Duration Parasympathetic Nervous System Purkinje Fiber Cholinergic Nerve Beta Adrenergic Blockade 
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Copyright information

© Martinus Nijhoff Publishers, Dordrecht 1987

Authors and Affiliations

  • John C. Bailey
  • Eric N. Prystowsky

There are no affiliations available

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