Venous compliance in essential hypertension

  • G. M. London
  • M. E. Safar
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 63)


The function of intravascular volume is to ensure the adequacy of the circulation, i.e. a cardiac output adapted to the metabolic needs of the tissues. The adequacy of the circulation depends on its filling pressure, especially on the filling pressure of the heart [1, 2]. For the overall circulatory system, a well-defined relationship must exist between changes in blood volume and changes in circulatory filling pressure [1]. The slope of the relationship between intravascular volume and pressure defines vascular compliance, which reflects the inherent elasticity of the vascular system [1, 2]. Changes in vascular. compliance are of primary importance in the control of cardiovascular function and extracellular fluid volume regulation [1, 2, 3].


Blood Volume Essential Hypertension Central Venous Pressure Intravascular Volume Total Blood Volume 
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© Martinus Nijhoff Publishers, Dordrecht. 1987

Authors and Affiliations

  • G. M. London
  • M. E. Safar

There are no affiliations available

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