Abstract
The morphological classifications of breast carcinomas have been inadequate in the assessment of response to the therapy or the prognosis of patients. Since the demonstration of a correlation of the estrogen receptor (ER) and the progesterone receptor (PR) status to the response to endocrine therapy (Muire 1975), disease free interval and survival (Knight et al. 1977; Blarney et al. 1980) in breast cancer, attempts have been made to find correlations between the ER and PR status and the histology of breast carcinomas (review, Underwood 1983).
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References
Alanko A., Mäkinen J., Scheinin T.M., Tolppanen E-M., and Vihko R., Correlation of estrogen and progesterone receptor and histological grade in human primary breast cancer. Acta Pathol. Microbiol. Immunol. Scand. Sect.A, 92, 311–315, 1984.
Ashorn P., and Krohn K., Characterization and partial purification of human milk fat globule membrane antigens by a polyacrylamide gel e1ectrophoreresis and immunoblotting using monoclonal antibodies. Int. J. Cancer, 35, 179–184, 1985.
Berry N., Jones D.B., Smallwood J., Taylor I., Kirkham N., and Taylor-Papadimitriou J., The prognostic value of the monoclonal antibodies HMFG1 and HMFG2 in breast cancer. Br. J. Cancer, 51, 179–186, 1985.
Blarney R.W., Bishop H.M., Blake J.R.S., Doyle P.J., Elston C.W., Haybittle J.L., Nicholson R.I., and Griffiths K., Relationship between primary breast tumor receptor status and patient survival. Cancer, 46., 2765–2769, 1980.
Bloom H.J.G., and Richardson W.W., Histological grading and prognosis in breast cancer: a study of 1409 cases of which 359 have been followed for 15 years. Br. J. Cancer, 11, 359–401,1957.
Fisher E.R., Gregorio R.M., and Fisher B., The pathology of invasive breast cancer. A syllabus from findings of the national surgical adjuvant breast project (protocol No.4). Cancer, 36, 1–85, 1975.
Fisher E.R., Osborne C.K,, Muire W.L., Redmond C., Knight III W.A., Fisher B., Bannayan G., Walder A., Gregory E.J., Jacobsen A., Queen D.M., Bennett D.E., and Ford H.C., Correlation of primary breast cancer histopathology and estrogen receptor content. Breast Cancer Res. Treat., 1, 37–41, 1981.
Fisher E.R., Redmond C.K., Liu H., Rockette H., Fisher B., and collaborating.NSABP investigators, Correlation of estrogen receptor and pathologic characteristics of invasive breast cancer. Cancer 45, 349–353, 1980.
Foster C.S., Dinsdale E.A.,Edwards P.A.W., and Neville M.A., Monoclonal antibodies to the human mammary gland II.Distribution of determinants in breast carcinomas. Virchows Arch. (Pathol Anat) 394, 295–305, 1982.
Haybittle J.L., Blarney R.W., Elston C.W., Johnson J., Doyle P.J., Campbell F.C., Nicholson R.I., and Griffiths K., A prognostic index in primary breast cancer. Br. J. Cancer, 45., 361–366, 1982.
Hilkens J., Buijs F.,Hilgers J., Hageman Ph., Calafat J., Sonnenberg A., and van der Valk M., Monoclonal antibodies against human milk–fat globule membranes detecting differentation antigen of the mammary gland and its tumors. Int. J. Cancer, 34, 197–206, 1984.
Knight III W.A., Livingston R.B., Gregory E.J., and Muire W.L., Estrogen receptor as an independent prognostic factor for early recurrence in breast cancer. Cancer Res., 37, 4669–4671, 1977.
Korenman S.G., and Dukes B.A., Spesific estrogen binding by the cytoplasm of human breast carcinoma. J. Clin. Endocrinol. 30, 639–645, 1970.
Krohn K., and Helle M., Recognition with a monoclonal antibody of a cytoplasmic mammary carcinoma antigen, correlated to the estrogen receptor status. Int. J. Cancer, 37., 43–47, 1986.
Krohn K., Ashorn R., and Helle M., Generation of monoclonal antibodies to human milk fat globule membrane antigens, with special reference to a precipitable secretory product of breast and ovarian carcinomas. Tumor Biology, 6, 13–23, 1985.
McGuire W.L., Current status of estrogen receptors in human breast cancer. Cancer, 36, 638–644, 1975.
McGuire W.L., Horwitz K.B., Zava D.T., Garola R.E., and Chamness G.C. Hormones in breast cancer: Update 1978. Metabolism, 27, 487–501, 1978.
Millis R.R., Correlation of hormone receptors with pathological features in human breast cancer. Cancer 46., 2869–2871, 1980.
Osborne C.K., Fisher E., Redmond C., Knight III W.A., Yochomowitz W.A., and Muire W.L., Estrogen receptor, a marker for human breast cancer differentation and patient prognosis. Adv. Exp. Med. Biol., 138, 377–385, 1980.
Rasmussen B., Hilkens J., Hilgers J., Nielsen H.H., Thorpe S.M., and Rose C., Monoclonal antibodies applied to primary human breast carcinoma: relationship to menopausal status, lymph node status, and steroid hormone receptor content. Breast Cancer Res. Treat.2 401–405, 1982.
Rich M.A., Furmanski P., and Brooks S.C.,and the breast cancer prognostic study surgery and pathology associates., Prognostic value of estrogen receptor determinations in patients with breast cancer. Cancer Res., 38, 4296–4298, 1978.
Taylor-Papadimitriou J., Peterson J.A., Arklie J., Burchell J. and Ceriani R.L., Monoclonal antibodies to epithelium-spesific component on the human milk fat globule membrane: production and reaction with cells in culture. Int. J. Cancer, 28, 17–21, 1981.
Westerberg H., Gustafson S.A., Nordenskjold B., Silfversward C., and Wallgren A., Estrogen receptor level and other factors in early recurrence of breast cancer, Int. J. Cancer, 26, 429–433, 1980.
WHO, International histological classification of tumors. Histological typing of breast tumours, No 2, Geneva, 17–22, 1981.
Wilkinson M.J.S., Howell A., Harris M., Taylor-Papadimitriou J., Swindell R., and Sellwood R.A., The prognostic significance of two epithelial membrane antigens expressed by human mammary carcinomas. Int. J. Cancer33, 299–304, 1984
Wittff J.L., Steroid–hormone receptors in breast cancer. Cancer, 53, 630–643, 1984.
Underwood J.C.E., Oestrogen receptors in human breast cancer: review of histopatho1ogica 1 correlations and critique of histochemica1 methods. Diagnostic Histopathology,6, 1–22, 1983.
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© 1986 Martinus Nijhoff Publishers, Dordrecht
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Helle, M., Antonen, J., Krohn, K. (1986). Relationship of the Estrogen Receptor Activation to the Histological Findings in Mammary Carcinoma. In: Hollmann, K.H., Verley, J.M. (eds) New Frontiers in Mammary Pathology 1986. Developments in Oncology, vol 49. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3297-5_18
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DOI: https://doi.org/10.1007/978-94-009-3297-5_18
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