Abstract
Enterotoxigenic strains of C. perfringens are now implicated in cases of diarrhoea other than food poisoning. There is good evidence that cross-infection may occur and that cross-infection control measures are helpful in limiting spread of the disease. The organism can be readily isolated from the immediate environment of affected patients as well as from their hands. In general the diarrhoea is self limiting, but metronidazole or vancomycin may be used to treat troublesome cases. Faecal blood and mucous and abdominal pain feature in about half of the cases.
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References
Barrison, I.G. and Kane, S.P. 1978. Penicillin- associated colitis. Lancet 2: 843.
Borriello, S.P. 1984. Bacteria and gastrointestinal secretion and motility. Scand. J. Gastroenterol. 19: 115–121.
Borriello, S.P. 1985. Newly described clostridial diseases of the gastrointestinal tract: Clostridium perfringens enterotoxin-associated diarrhoea and neutropenic enterocolitis due to Clostridium septicum. In: S.P. Borriello (ed). Clostridial Diseases of the Gastrointestinal Tract. CRC Press Inc. Florida. p. 223.
Borriello, S.P., Barclay, F.E., Welch, A.R., Stringer, M.F., Watson, G.N., Williams, R.K.T., Seal, D. V. and Sullens, K. 1985. Epidemiology of diarrhoea caused by enterotoxigenic Clostridium perfringens. J. Med. Microbiol. 20: 363–372
Borriello, S.P., Larson, H.E., Welch, A.R., Barclay, F., Stringer, M.F. and Bartholomew, B.A. 1984. Enterotoxigenic Clostridium perfringens: A possible cause of antibiotic-associated diarrhoea. Lancet 1: 305–307.
Borriello, S.P., Welch, A.R., Larson, H.E. and Barclay, F.E. 1984. Diarrhoea and simultaneous excretion of Clostridium difficile cytotoxin and C.perfringens enterotoxin. Lancet. 2: 1218.
Borriello, S.P. and Williams R.K.T. 1985. Treatment of Clostridium perfringens enterotoxin-associated diarrhoea with metronidazole. J. infect. 10: 65–67.
McDonel, J.L. and Demers, G.W. 1982. In vivo effects of enterotoxin from Clostridium perfringens Type A in the rabbit colon: Binding vs. biological activity. J. Infect. Dis. 145: 490–494
Sakurai Y., Tsuchiya, H., Ikegami, F., Funatomi, T., Takasu, S. and Uchikoshi, T. 1979. Acute right-sided hemorrhagic colitis associated with oral administration of ampicillin. Dig. Dis. Sci. 24: 910–915.
Toffler, R.B., Pingoud, E.G. and Burrell, M.I. 1978. Acute colitis related to penicillin and penicillin derivatives. Lancet 2: 707–709.
Williams, R., Piper, M., Boriello, S.P., Barclay, F., Welch, A., Seal, D. and Sullens, K. 1985. Diarrhoea due to entero-toxigenic Clostridium perfringens: Clinical features and management of a cluster of 10 cases. Age and ageing 14: 296–302.
Yamagishi, T., Serikawa, T., Morita, R., Nakamura, S. and Nishida, S. 1976. Persistent high numbers of Clostridium perfringens in the intestines of Japanese aged adults. Jap. J. Microbiol. 20: 397–403.
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© 1987 Martinus Nijhoff Publishers, Dordrecht
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Borriello, S.P., Larson, H.E., Barclay, F.E., Welch, A.R. (1987). Clostridium Perfringens Enterotoxin-Associated Diarrhoea. In: Borriello, S.P., Hardie, J.M., Drasar, B.S., Duerden, B.I., Hudson, M.J., Lysons, R.J. (eds) Recent Advances in Anaerobic Bacteriology. New Perspectives in Clinical Microbiology, vol 12. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3293-7_4
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DOI: https://doi.org/10.1007/978-94-009-3293-7_4
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