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Abstract

The fear experienced by the animal in an experimental situation may distort the results of the experiment. Although handling is known to influence the animals’ reactions, this fact has been largely ignored in behavioural studies. We studied the effects of gentling on behaviour of rats in three fundamentally different open-field situations: stressful, indifferent and frightening.

90 male Kuo:Wistar rats, aged 95 days, were tested on openfield for 5 min. on 4 successive days. 3 weeks before testing the rats were randomly divided into two groups: one to be individually gentled and the other to be left with routine care only.

The behaviour in all the groups was typical to the test situation. A basic difference was found in the behaviour of the gentled and nongentled rats. While all the rats showed a slight and transient fear of the new situation, the nongentled ones also showed a different type of fear, suggesting fear towards the experimenter.

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References

  1. Broadhurs P.L.,: Determinants of Emotionality in the Rat: I. Situational Factors. British Journal of Psychology, 48, 1–2, 1957.

    Article  Google Scholar 

  2. Bustad L.K.,: Laboratory Animal Scientists and Their New Role in Human-Animal Bonding. The 8 t h ICLAS/CALAS Symposium, Vancouver, 1983.

    Google Scholar 

  3. Candland DK, Faulds B, Thomas DB and Candland MH: The Reinforcing Value of Gentling. Journal of Comparative and Physiological Psychology, 53, 55–58, 1960.

    Article  PubMed  CAS  Google Scholar 

  4. Candland DK, Horowitz SH and Culbertson JL: Acquisition and Retention of Acquired Avoidance with Gentling as Reinforcement. Journal of Comparative and Physiological Psychology, 55, 1062–1064, 1962.

    Article  PubMed  CAS  Google Scholar 

  5. Corda MG, Biggio G and Gessa LG: Brain Nucleotides in Naive and Handling-habituated Rats: Differences in Levels and Drug-sensitivity. Brain Research, 188, 287–290, 1980.

    Article  PubMed  CAS  Google Scholar 

  6. Hirsjarvi PA and Junnila MA: Effects of Light and Noise Test Stimuli on the Open-field Behaviour of Wistar Rats. Scandinavian Journal of Psychology, 27, 311–319, 1986.

    Article  Google Scholar 

  7. Hughes C.W.,: Observer Influence on Automated Open-field Activity. Physiology and Behavior, 20, 481–485, 1978.

    Article  PubMed  CAS  Google Scholar 

  8. Hughes RN and Beveridge IJ: Effects of Experimental and Test Location Novelty on Nonspesific Activity in Rats and Its Modification by Metamphetamine. New Zealand Psychologist, 9, 15–18, 1980.

    Google Scholar 

  9. McCall RB, Lester ML and Corter CM: Caretaker Effect in Rats. Developmental Psychology, 1, 771, 1969.

    Article  Google Scholar 

  10. Meaney MJ, Aithen DH, Bodnoff SR, Iny LJ, Tatarewicz JE and Sapolsky RM: Early Postnatal Handling Alters Glucocorticoid Receptor Concentrations in Selected Brain Regions. Behavioral Neuroscience, 99, 765–770, 1985.

    Article  PubMed  CAS  Google Scholar 

  11. Uphouse L.L.,: Interactions between Handling and Acrylamide on the Striatal Dopamine Receptor. Brain Research, 221, 421–424, 1981.

    Article  PubMed  CAS  Google Scholar 

  12. Uphouse LL, Nemeroff CB, Mason G, Prange AJ and Bondy SC: Interactions between ‘Handling’ and Acrylamide on Endocrine Responses in Rats. Neurotoxicology, 3, 121–125, 1982.

    PubMed  CAS  Google Scholar 

  13. Walsh RN and Cummins RA: The Open-field Test: A Critical Review. Psychological Bulletin, 83, 482–504, 1976.

    Article  PubMed  CAS  Google Scholar 

  14. Williams DJ and Russell PA: Open-field Behaviour in Rats Effects of Handling, Sex and Repeated Testing. British Journal of Psychology, 63, 593–596, 1972.

    Article  PubMed  CAS  Google Scholar 

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© 1988 Martinus Nijhoff Publishers, Dordecht

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Hirsjärvi, P.A., Junnila, M.A. (1988). The Effects of Gentling on Open-field Behaviour of Rats. In: Beynen, A.C., Solleveld, H.A. (eds) New Developments in Biosciences: Their Implications for Laboratory Animal Science. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3281-4_64

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  • DOI: https://doi.org/10.1007/978-94-009-3281-4_64

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7973-0

  • Online ISBN: 978-94-009-3281-4

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