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Immunology of Malignant Diseases pp 151–166Cite as

Immunological Features of Human Bladder Cancer

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Part of the book series: Immunology and Medicine ((IMME,volume 6))

Abstract

Bladder carcinoma is globally one of the ten most common types of malignant diseases, being more than twice as frequent in men as in women. In contrast to some other carcinomas such as colon carcinoma, the frequency of bladder cancer is showing a world-wide increase, in several areas being as high as 100% over the last 20 years. The exact aetiology is unknown but a relationship to cigarette smoking and to the exposure to certain chemical substances (e.g. β-naphthylamine, benzidine) has been demonstrated1,2. In the great majority of cases (>95%) tumours arise in the transitional epithelium of the bladder wall, ureter or renal pelvis and the disease is often referred to as transitional cell carcinoma (TCC). Treatment has generally been performed by transurethral resection or irradiation but successful therapy of superficial tumours has also been achieved with intravesical instillations of chemotherapeutic agents3. Regardless of the type of treatment, prognosis is closely dependent on the stage and malignancy of the individual tumours stressing the importance of early and accurate diagnosis.

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Authors and Affiliations

  1. Department of Immunology, University of Stockholm, S-10691, Stockholm, Sweden

    S. Paulie & P. Perlmann

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  1. S. Paulie
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  2. P. Perlmann
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Editors and Affiliations

  1. Xoma Corporation, Berkeley, California, USA

    V. S. Byers

  2. Cancer Research Campaign Laboratories, University of Nottingham, Nottingham, UK

    R. W. Baldwin

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© 1987 MTP Press Limited

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Paulie, S., Perlmann, P. (1987). Immunological Features of Human Bladder Cancer. In: Byers, V.S., Baldwin, R.W. (eds) Immunology of Malignant Diseases. Immunology and Medicine, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3219-7_9

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  • DOI: https://doi.org/10.1007/978-94-009-3219-7_9

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7945-7

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