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Prostaglandins and leukotrienes and the fetal and perinatal circulations

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Eicosanoids and Reproduction

Part of the book series: Advance in Eicosanoid Research ((AEIR,volume 1))

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Abstract

Several metabolites of arachidonic acid are important in maintaining the integrity of the fetal and neonatal circulations. The cyclo-oxygenase mediated metabolites, the prostaglandins (PGs) and thromboxane (Tx) have received most attention. However, recent studies indicate that the leukotrienes (LTs), the 5′-lipoxygenase mediated products of arachidonic acid, play an equally important role, both groups perhaps affecting different fetal structures or vascular beds, as well as perhaps interacting in the regulation of flow in some.

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  1. Clinical Pharmacology Group, Medical Faculty, University of Southampton, UK

    Keith Hillier (Senior Lecturer) (Senior Lecturer)

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Heymann, M.A. (1987). Prostaglandins and leukotrienes and the fetal and perinatal circulations. In: Hillier, K. (eds) Eicosanoids and Reproduction. Advance in Eicosanoid Research, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3215-9_11

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  • DOI: https://doi.org/10.1007/978-94-009-3215-9_11

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