Abstract
Tumors of the soft tissue and bone, classified as mesenchymal tumors, are relatively rare; the annual incidence in the United States is fewer than 5,000 cases. A major proportion of these tumors occur in the pediatric age group in the form of osteogenic or other bone sarcomas and rhabdomyo sarcomas. The adult types of sarcomas are the soft tissue variants, dominated by the malignant fibrohistiocytoma. The natural history and clinical behavior of the various categories of soft tissue sarcomas are related to the stage and histologic grade of the tumor, site of the primary tumor and, to some extent, the pathologic subtype.
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References
Bramwell VHC, Mouridron HT, Malder JH, et al. Carminomycin versus Adriamycin in advanced soft tissue sarcoma. Eur J Cancer Clin Oncol 1983; 19: 1097.
Gottleib JA, Baker LH, O’Bryan RM, et al. Adriamycin used alone in combination for soft tissue and bony sarcomas. Cancer Chemother Rep 1975; 6(3): 271–82.
Subramanian S, Wiltshaw E. Chemotherapy of sarcoma. A comparison of three regimens. Lancet 1978; 683–86.
Rosenberg SA, Suit HD, Baker LH, Rosen G. Sarcomas of the soft tissue and bone. In: Cancer- principles and practice of oncology. Devita VT Jr., Hellman S, Rosenberg SA, eds. Philadelphia: JB Lippincott 1982; 1036–93.
Stuart-Harris RC, Harper PG, Parsons CA, et al. High-dose alkylation therapy using ifosfamide infusion with mesna in the treatment of adult soft tissue sarcoma. Cancer Chemother Pharmacol 1983; 11: 69.
Burkett H. Ifosfamide: European perspective. Sem Oncol (Suppl. 1) 1983; 9: 28.
Cortes EP, Holland JF, Wang JJ, et al. Adriamycin (NSC-123127) in 87 patients with osteosarcoma. Cancer Chemother Rep 1975; 6: 305–13.
Pratt CB, Champion JE, Senzer N, et al. Treatment of unresectable or metastatic osteosarcoma with cisplatin and cisplatin-doxorubicin. Cancer 1985; 56: 1930–33.
Ochs JJ, Freeman Al, Douglass HO Jr., et al. Cis-dichlorodiammineplatinum (II) in advanced osteogenic sarcoma. Cancer Treat Rep 1978; 62: 239–45.
Rosen G, Nirenberg A, Caparros B. Evaluation of high dose methotrexate (HDMTX) with citrovorum factor rescue (CER) single agent chemotherapy in osteogenic sarcoma (OSA). Proc AACR 1980; March: 177.
Rosen G, Caparros B, Huvos AG, et al. Preoperative chemotherapy for osteogenic sarcoma: selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy. Cancer 1982; 49: 1221–30.
Eilber FR, Grant T, Morton DL. Adjuvant therapy for osteosarcoma: preoperative and postoperative treatment. Cancer Treat Rep 1978; 62: 213–16.
Eilber FR, Morton DL, Eckardt J, Grant T, Weisenburger T. Limb salvage for skeletal and soft tissue sarcomas. Cancer 1984; 53: 2579–84.
Azzarelli A, Quaglinolo V, Audiso RA, Boufouti G, Audreola S, Gemari L. Intra-arterial Adriamycin followed by surgery for limb sarcomas: preliminary report. Eur J Cancer Clin Oncol 1983; 19: 885–90.
Jaffe N, Bowman R, Wang Y, et al. Chemotherapy for primary osteosarcoma by intra-arterial infusion: review of the literature and comparison of results achieved by the intravenous route. Cancer Bull 1984; 36: 37–41.
Campbell TN, Howell SB, Pfeifle CE, Wung WE, Bookstein J. Clinical pharmacokinetics of intra-arterial cisplatin in humans. J Clin Oncol 1983; 1: 755–62.
Jaffe N, Knapp J, Chuang VP, et al. Osteosarcoma: intra-arterial treatment of primary tumor with cisplatin. Cancer 1983; 51: 402.
Benjamin RS, Chawla SP, Murray JP, et al. Response to preoperative chemotherapy of osteosarcoma improves disease-free survival and the chances of limb salvage. Proc AACR 1985; 26: 174.
Jaffe N, Prudich J, Knapp J, et al. Treatment of primary osteosarcoma with intra-arterial and intravenous high-dose methotrexate. J Clin Oncol 1983; 1: 428.
Akahoshi Y, Takeuchi S, Chen S, et al. The results of surgical treatment combined with intraarterial infusion of anticancer agents in osteosarcoma. J Clin Orthop 1976; 120: 102–09.
Legha SS, Benjamin RS, MacKay B, et al. Role of Adriamycin in breast cancer and sarcomas. In: Anthracycline antibiotics in cancer therapy. Muggia FM, Young CW, Carter SK, eds. Marinus Nijhoff Publishers, 1982; 432–44.
Lokich JJ, Bothe A, Gaj E, Rich T. Protracted systemic infusion of doxorubicin: studies in 83 patients with advanced malignancy. Cancer Treat Symp 1984; 3: 85–89.
Gasparini M, Rouesse J, Van Oosterom A, et al. Phase 2 study of cisplatin in advanced osteogenic sarcoma. Cancer Treat Rep 1985; 69: 211–13.
Gasparini M, Fossati B, Rottali L, Grairi C, Azzarelli A. Remission induction by chemotherapy (VCR, HDMTX, CDDP) in osteosarcoma. Proc ASCO 1983; 2: 239.
Yap BS, Benjamin RS, Plager C, Burgess MA, Papdoupolos N, Bodey GP. A randomized study of continuous infusion vindesine versus vinblastine in adults with refractory sarcomas. Am J Clin Oncol 1983; 6: 235–38.
Rosenberg SA. Prospective randomized trials demonstrating the efficacy of adjuvant chemotherapy in adult patients with soft tissue sarcomas. Cancer Treat Rep 1984; 68: 1067–78.
Rosen G, Nirenberg A. Chemotherapy for primary osteogenic sarcoma: ten year evolution, and current status of preoperative chemotherapy. Adjuvant Ther Cancer 1984; IV: 593–629.
Posner MR, Belliveau JF, Ferrari L, et al. Clinical and pharmacokinetic study of 5-day continuous infusion cis-platinum. Proc ASCO 1985; 4: C-145.
Rosenthal CJ, Park HS, Choi K, Bhutiani I, Rotman M. Effective therapy for advanced localized soft tissue sarcomas (STS): Adriamycin (ADR) by continuous infusion (CI) and concomitant radiation therapy (RT). Proc ASCO 1985; 4: C–565.
Bonadonna G, Santoro A. Bone and soft tissue sarcoma. In: Cancer chemotherapy annual 6. Pinedo HM, Chabner BA, eds. Elsevier Science Publishers B.V., 1984; 25: 436–49.
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Lokich, J.J., Lackman, R., Weiss, A.J. (1987). Soft Tissue and Osteogenic Sarcomas. In: Cancer Chemotherapy by Infusion. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3193-0_29
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DOI: https://doi.org/10.1007/978-94-009-3193-0_29
Publisher Name: Springer, Dordrecht
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