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Abstract

The well-known resistance of nonoat cell lung carcinomas to conventional forms of chemotherapy has led us, since 1979, to use continuous, prolonged infusions of cytostatic drugs in order to try to overcome the kinetic resistance and to prolong the inhibition of DNA repair without increasing the toxicity. This chapter reports several consecutive phase 2 trials conducted in collaboration with members of the French Thoracic Oncology club.* All were based on a combination of cisplatin and bleomycin.

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© 1987 Precept Press, Inc.

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Israel, L., Breau, JL., Morere, J.F. (1987). Lung Cancer. In: Cancer Chemotherapy by Infusion. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3193-0_26

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  • DOI: https://doi.org/10.1007/978-94-009-3193-0_26

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7932-7

  • Online ISBN: 978-94-009-3193-0

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