Abstract
Bucher et al.1 have reported the synergistic hepatotrophic action of glucagon and insulin in eviscerated partially hepatectomized rats. Likewise, Farivar et al.2 also demonstrated that mortality is reduced in mice infected with murine hepatitis virus when both glucagon and insulin are administered.
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References
Bucher NLR, Swaffield MN. Regulation of hepatic regeneration in rats by synergistic action of insulin and glucagon. Proc Natl Acad Sci USA 1987; 72: 1157–1160.
Farivar M, Wands JR, Isselbacher KJ, Bucher NLR. Effect of insulin and glucagon on fulminant murine hepatitis. N Engl J Med 1976; 295: 1517–1519.
Baker AL, Jaspan JB, Haines NW, Hatfield GE, Krager PS, Schneider JF. A randomized clinical trial of insulin and glucagon infusion for treatment of alcoholic hepatitis. Progress report in 50 patients. Gastroenterology 1981; 80: 1410–1414.
Baker AL. Insulin and glucagon for liver disease. Assessment of response in patients with alcoholic hepatitis. In: Picazo J, ed. Glucagon in Gastroenterology and Hepatology. Lancaster: MTP Press, 1982: 155–169.
Okiita K, Matsuda S, Hata K, Morimoto T, Sasaki M, Fukumoto Y, Kodama T, Takemoto T. Clinical use of glucagon and insulin in therapy of fulminant hepatic failure. Gastroenterol Jpn 1979; 14: 453–457.
Oka H, Okita K, Fujiwara K, Glucagon and insulin therapy in fulminant hepatic failure in Japan. In: Picazo J, ed. Glucagon in Gastroenterology and Hepatology. Lancaster: MTP Press, 1982: 171–180.
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© 1987 MTP Press Limited
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Oka, H., Fujiwara, K., Okita, K., Ishii, H., Sakuma, A. (1987). Clinical evaluation of glucagon—insulin therapy for acute hepatitis severe form. In: Picazo, J. (eds) Glucagon in 1987. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-3185-5_9
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DOI: https://doi.org/10.1007/978-94-009-3185-5_9
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-7929-7
Online ISBN: 978-94-009-3185-5
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