Comment on Michael Ruse’s Essay
Professor Ruse deals with the question of the interruption of clinical trials when he refers to “sequential testing” by which a trial is “cut off” when a certain level of statistical significance has been reached. In essence, however, his discussion applies to a wider scope, that of the level of statistical significance demanded in clinical trials in general (not only sequential ones) including those where the endpoint-time is preset. Thus, although the title of his essay may seem too narrow for its content, the wider scope of the analysis makes it the richer.
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