Abstract
The different types of neoplasms must be seen as specific, individual diseases, because “cancer” is not one disease but a group of many. The single neoplastic types exhibit type-specific characteristics, of which the pattern of metastasis is the one most important for the fate of the patient. I consider as pattern of metastasis not only the tumor-specific distribution of secondary neoplastic growth, but also the circumstances leading to the tumor performance when it has approached the secondary growth phase. It is not only the histologic characteristic or the type of metastatic spreading which results in the pattern of the secondary neoplasm throughout the body. There are many factors involved and they vary from tumor to tumor, if several tumors in one or more species are compared. But even the neoplastic pattern of the metastatic distribution of one tumor shows a variability (at least in many cases) between common characteristics of its metastasis, and variable. The metastatic pattern also shows heterogeneity of distribution, which may be one reason why the path of metastasis of many tumor types is so unpredictable.
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Kaiser, H.E. (1989). Pattern of Metastasis. In: Gorelik, E.L. (eds) Metastasis / Dissemination. Cancer Growth and Progression, vol 8. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2534-2_2
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DOI: https://doi.org/10.1007/978-94-009-2534-2_2
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