Abstract
Diagnostic procedures in inflammatory bowel disease should provide information about:
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Type of disease (Crohn’s disease, ulcerative colitis, etc.)
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Localization
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Activity grading
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Complications (abscesses, fistulae, joint disease)
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Disorders of bowel function.
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References
McAffee, J.G. and Thakur, M.L. (1976). Survey of radioactive agents for in vivo labelling of phagocytic leukocytes. I. Soluble agents. J. Nucl. Med., 17, 480–7
McAffee, J.G. and Thakur, M.L. (1987). Survey of radioactive agents for in vivo labelling of phagocytic leukocytes. II. Particles. J. Nucl. Med., 17, 488–92
Thakur, M.L., Coleman, R.E., Mayhall, C.G. and Welch, M.J. (1976). Preparation and evaluation of In-111 labelled leukocytes as an abscess imaging agent in dogs. Radiology, 119, 731–2
Thakur, M.L., Lavender, J.P. and Arnot, R.N. (1977). Indium-111 labelled autologous leukocytes in man. J. Nucl. Med., 18, 1012–19
Becker, W., Fischbach, W., Reiners, C. and Borner, W. (1985). 111In-Oxin markierte Leukozyten: Eine Methode zur Lokalisationsdiagnostik und Aktivitätsbeurteilung von Morbus Crohn und Colitis ulcerosa. Z. Gastroenterol., 23, 557–64
Saverymuttu, S.H., Peters, A.M., Hodgson, HJ. and Chadwick, V.S. (1983). Assessment of disease activity in ulcerative colitis using 111-indium labelled leukocyte faecal excretion. Scand. J. Gastroenterol., 18, 907–12
Paul, J.L., Moissan, A., Cardin, U.L., Le Cloirec, J., Herry, J.H. and Launoise, B. (1985). Recherche des collections suppuries intra-abdominales. Presse Med, 29, 1367–70
Saverymuttu, S.H., Crofton, M.E., Peters, A.M. and Lavender, J.P. (1983). Indium-111 tropolonate leukocyte scanning in the detection of intraabdominal abscesses. Clin. Radiol., 34 593–6
Becker, W., Fischbach, W., Reiners, C. and Borner, W. (1985). 111In-Oxin markierte Granulozyten bei Morbus Crohn und Colitis ulcerosa — Markierungs- und Untersuchungstechnik. RöFo, 142, 320–5
Saverymuttu, S.H., Peters, A.M., Crofton, M.E., Rees, H., Lavender, J.P., Hodgson, H.J. and Chadwick, V.S. (1985). 111-Indium autologous granulocytes in the detection of inflammatory bowel disease. Gut, 26, 955–60
Becker, W., Schomann, E., Fischbach, W., Börner, W. and Grüner, K.R. (1988). Comparison of 99mTc HMPAO and 111In-oxine labelled granulocytes in man: first clinical results. Nucl. Med. Commun., 9, 435–47
Joseph, J., Höffken, H., Bosslet, K. and Schorlemmer, H.U. (1988). In vivo labelling of granulocytes with 99mTc anti-NCA monoclonal antibodies for imaging inflammation. Eur. J. Nucl. Med., 7/8, 367–73
Kroiss, A., Weiss, W., Kölbl, Ch., Dinstl, K. and Neumayr, A. (1988). Neue diagnostische Möglichkeiten bei M. Crohn und Colitis ulcerosa mit 123-J markierten anti-Granulozyten Antikörpern. Nucl. Med., 2, 19
Sfakianakis, G.N., Al-Seikh, W., Heal, A., Rodman, G., Zeypa, R. and Serafini, A. (1982). Comparison of scintigraphy with In-111 leukocytes and 67Ga in the diagnosis of occult sepsis. J. Nucl. Med., 23, 618–26
Kadir, S. and Strauss, H.W. (1976). Evaluation of inflammatory bowel disease with 99mTc DTPA. Radiology, 130, 443–6
Abdel-Dayem, H.M., Mahajan, K.K., Ericsson, S.B.S., Kouris, K., Owunwanne, A., Nawaz, K., Higazi, E. and Awdeh, M. (1986). 99mTc-DTPA uptake in malignant and inflammatory bowel disease: experience from intestinal bleeding studies. Nucl. Med. Commun., 7, 381–9
Dawson, DJ., Khan, A.N., Nutall, P. and Shreeve, D.R. (1985). Technetium-99m labelled sucralphate isotope scanning in the detection of peptic ulceration. Nucl. Med. Commun., 6, 319–25
Vasquez, T.E., Bridges, R.L., Braunstein, P., Jansholt, A.L. and Meshkinpour, H. (1983). Gastrointestinal ulcerations: detection using a technetium-99m-labelled ulcer-avid agent. Radiology, 148, 227–31
Crama-Bohbouth, G.E., Arndt, J.W., Pena, A.S., Blok, D., Verspaget, H.W., Weterman, I.T., Lamers, C.B.H.W. and Pauwels, E.K.J. (1988). Is radiolabelled sucralphate scintigraphy of any use in the diagnosis of inflammatory bowel disease? Nucl. Med. Commun., 9, 591–5
Khan, A.N., Miller, V., Ratcliffe, J.F. and Dawson, DJ. (1985). Technetium-99m-sucralphate isotope scanning in the detection of active inflammatory bowel disease in children. Eur. J. Nucl. Med., 2/3, A33
Christian, P.E., Datz, F.L., Sorensen, JA. and Taylor, A. (1983). Technical factors in gastric emptying studies: teaching editorial. J. Nucl. Med., 3, 264–8
Malagelada, J.R., Robertson, J.S., Brown, M.L., Remington, M., Duenes, J.A., Thornforde, G.M. and Carryer, P.W. (1984). Intestinal transit of solid and liquid components of a meal in health. Gastroenterology, 87, 1255–63
Grill, B.B., Lange, R., Markowitz, R., Craig Hillemeier, A, McCallum, R.W. and Gryboski, J.D. (1985). Delayed gastric emptying in children with Crohn’s disease. J. Clin. Gastroenterol., 7, 216–26
Lorenz-Meyer, H. and Brandes, W. (1981). Klinik des Morbus Crohn. Internist, 22, 420–9
Mekhjian, H.S., Switz, D.M., Melnyk, C.S., Rankin, G.B. and Brooks, R.K. (1979). Clinical features and natural history of Crohn’s disease. Gastroenterology, 77, 898–906
Rankin, J.B., Watts, H.D., Melnyk, C.S. and Kelley, M.L. (1979). National co-operative Crohn’s disease study: extraintestinal manifestations and perianal complications. Gastroenterology, 77, 914–20
Agnew, J.E., Pocock, D.G. and Jewell, D.P. (1982). Sacroiliac joint ratios in inflammatory bowel disease: relationship to backpain and to activity of bowel disease. Br. J. Radiol., 55, 821–6
Boyd, G.S., Merrick, M.V., Monks, R. and Thomas, I.L. (1981). Se-75 labelled bile acid analogs, new radiopharmaceuticals for investigating the enterohepatic circulation. J. Nucl. Med., 22, 720–5
Freundlieb, O., Szy, D., Balzer, K. and Strötges, M.W. (1983). Vergleichende Untersuchung über verschiedene Mebverfahren zur Beurteilung der Gallensäure-ausscheigung mitteis 75-Selen markierter Homotaurocholsäure (75-SeHCAT). Nucl. Med., 5, 258–61
Holdstock, G., Phillips, G., Harnes, T.K., Condon, B.R., Fleming, J.S., Smith, C.L. and Ackery, D.M. (1985). Potential of SeHCAT retention as an indicator of terminal ileal involvement in inflammatory bowel disease. Eur. J. Nucl. Med., 10, 528–30
Merrick, M.V., Eastwood, M.A. and Ford, M.J. (1985). Is bile acid malabsorption underdiagnosed? An evaluation of accuracy of diagnosis by measurement of SeHCAT retention. Br. Med. J., No. 6469, 665–8
Schilling, R.F. (1953). Intrinsic factor studies. J. Lab. Clin. Med., 42, 860–8
Lindstedt, S. (1957). The turnover of cholic acid in man. Act. Physiol. Scand., 40, 1–9
Hepner, G.W. (1975). Increased sensitivity of the cholyglycine breath test for detecting ileal dysfunction. Gastroenterology, 68, 8–16
Fromm, H., Thomas, P.J. and Hofmann, A.F. (1973). Sensitivity and specificity in tests of distal ileal function: prospective comparison of bile acid and vitamin B12 absorption in ileal resection patients. Gastroenterology, 64, 1077–90
Bjarnason, J., O’Morain, C., Levi, A.J. and Peters, T.J. (1983). Absorption of 51-chromium labelled ethylenediamine tetraacetate in inflammatory bowel disease. Gastroenterology, 85, 318–22
Bjarnason, J., Smethurst, P., Levi, A.J. and Peters, T.J. (1985). Intestinal permeability of Cr-EDTA in rats with experimentally induced enteropathy. Gut, 26, 579–85
Gordon, R.S. (1959). Exudative enteropathy: abnormal permeability of the gastrointestinal tract demonstrable with labelled polyvinylpyrrolidone. Lancet, 1, 325–6
Laster, L., Waldmann, T.A., Fenster, L.F. and Singleton, J.W. (1966). Albumin metabolism in patients with Whipple’s disease. J. Clin. Invest., 45, 637–44
Goldberg, H.J., Caruthers Jr., S.B., Nelson, JA. and Singleton, J.W. (1979). Radiographic findings of the national cooperative Crohn’s disease study. Gastroenterology, 77, 925–37
Becker, W., Fischbach, W., Reiners, C. and Borner, W. (1986). Three-phase white blood cell scan: diagnostic validity in abdominal inflammatory diseases. J. Nucl. Med., 27, 1109–15
Saverymuttu, S.H., Peters, A.M., Hodgson, H.J., Chadwick, V.S. and Lavender, J.P. (1983). 111-Indium leukocyte scanning in small bowel Crohn’s disease. Gastrointest. Radiol., 8, 157–61
Saverymuttu, S.H., Hodgson, H.J. and Chadwick, V.S. (1985). Controlled trial comparing prednisolone with an elemental diet plus non-absorbable antibiotics in active Crohn’s disease. Gut, 26, 994–8
Stein, D.T., Gray, G.M., Gregory, P.B., Anderson, M., Goodwin, DA. and Ross McDougall, I. (1983). Location and activity of ulcerative and Crohn’s colitis by indium-111 leukocyte scan. Gastroenterology, 94, 388–93
Ybern, A., Martin-Cornin, H., Gine, J.J., Casanovas, T., Villa, R. and Gassull, MA. (1986). 111-In-oxine labelled autologous leukocytes in inflammatory bowel disease: a new scintigraphic activity index. Eur. J. Nucl. Med., 111, 341–4
Best, W.R., Bectel, J.M., Singleton, J.W. and Kern, F. (1976). Development of a Crohn’s disease activity index. National co-operative Crohn’s disease study. Gastroenterology, 70, 439–44
Best, W.R., Bectel, J.M. and Singleton, J.W. (1979). Rederived values of the eight coefficients of the Crohn’s disease activity index (CDAI). Gastroenterology, 77, 843–6
Saverymuttu, S.H., Lavender, J.P., Hodgson, H.J. and Chadwick, V.S. (1983). Assessment of disease activity in inflammatory bowel disease: a new approach using 111-indium granulocyte scanning. Br. Med. J., 287, 1751–3
Scheurien, G, Kruis, W., Moser, E. and Paumgartner, G. (1988). Accuracy of whole body retention half-life of 75-SeHCAT in the diagnosis of ileal dysfunction in patients with Crohn’s disease. Hepato-Gastroenterology, 35, 136–9
Fagan, C.A., Chadwick, V.S. and McLean Baird, J. (1983). SeHCAT absorption: A simple test of ileal dysfunction. Digestion, 26,159–65
Nyhlin, H., Merrick, M.V., Eastwood, MA. and Brydon, W.G. (1983). Evaluation of ileal function using 23-selena-25-homotaurocholate, a gamma-labelled conjugated bile acid -clinical assessment. Gastroenterology, 84, 63–8
Thaysen, E.H., Orholm, M., Amfred, T., Carl, J. and Rödbro, P. (1982). Assessment of ileal function by abdominal counting of the retention of a gamma emitting bile acid analogue. Gut, 23, 862–5
Knockel, J.Q., Koehler, P.R., Lee, T.G. and Welch, J.M. (1980). Diagnosis of abdominal abscesses with computed tomography, ultrasound and 111In leukocyte scans. Radiology, 137, 425–32
Krestin, G.P., Beyer, D. and Steinbrich, W. (1984). Rationelles Vorgehen bei der Diagnostik abdomineller Abszesse mit Hilfe bildgebender Verfahren. RöFö, 141, 673–7
Lane, LR, Poskitt, K., Irwin, J.T.C., Sinclair, M., Jewkes, R.I. and McCollum, C.N. (1985). Abscess diagnosis using 111In leukocytes. Eur. J. Nucl. Med., 2/3, A26
Farivar, S., Fromm, H., Schindler, D., McJunkin, B. and Schmidt, F.W. (1980). Tests of bile acid and vitamin B12 metabolism in ileal Crohn’s disease. Am. J. Clin. Pathol., 73, 69–74
Holmquist, L., Anderssen, H., Rudic, N., Ahren, C. and Fällström, S.P. (1986). Bile acid malabsorption in children and adolescents with chronic colitis. Scand. J. Gastroenterol., 21, 87–92
Becker, W., Fischbach, W. and Börner, W. (1985). Autologous 111In-oxine labelled granulocytes in Yersinia infections. Eur. J. Nucl. Med., 10, 377–8
Mahlstedt, J., Habe, A., Wolf, F., Reichert, M., Duering, A., Herbst, M. and Stoll, R. (1985). Evaluation of small bowel injury after radiotherapy by radioisotopic test. Nucl. Med. Commun., 6, 601–2
Singleton, J.W. and Klingensmith III, W.C. Editorial (1983). Indium-111 leukocyte imaging study in inflammatory bowel disease. Gastroenterology, 2, 426–7
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© 1989 Kluwer Academic Publishers
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Bares, R., Buell, U. (1989). Nuclear medicine procedures in diagnosing inflammatory bowel disease. In: Matern, S. (eds) Clinical Research in Gastroenterology 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2488-8_1
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DOI: https://doi.org/10.1007/978-94-009-2488-8_1
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