Summary and Conclusions

  • Marc De Schrijver
Part of the Developments in Nuclear Medicine book series (DNUM, volume 16)


After intravenous injection, 99mTc-labelled nanocolloids are rapidly removed from the circulation by uptake in the reticuloendothelial system. During their passage at sites of inflammation, a fraction of the plasma-borne colloid dose extravasates through dehiscences of the vascular endothelium, traverses the discontinuous basement membrane and invades the basic intercellular substance, as has been demonstrated by experimental and clinical data.


99mTc DTPA Intercellular Substance Colloid Accumulation Label Leukocyte Discontinuous Basement 
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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • Marc De Schrijver
    • 1
  1. 1.Radiopharmaceutical DivisionSolco Basle Ltd.BasleSwitzerland

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