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Proliferation of Glomerular Cells

  • Chapter
Glomerulonephritis

Part of the book series: New Clinical Applications: Nephrology ((NCNG,volume 11))

Abstract

Proliferaiive nephritis is an old term and one often used loosely to mean glomerular hypercellularity. It has featured prominenlly in pathological classifications of nephritis since the systematic studies of Volhard and Farr.1 Individual types of proliferative nephritis are described in detail elsewhere in this series, and it is not the purpose of this chapter to reiterate these discussions; but rather to consider glomerular proliferation more generally. This is especially pertinent now for two reasons: first because recent clinical and experimental studies have defined the cellular composition of glomeruli much more accurately than has previously been possible; and secondly because of the wealth of information about the control of cell proliferation that has emerged from in vitro studies over the past 5 years. These emphasize the close links between factors controlling cell proliferation, acute inflammaiion and synthesis of the extracellular matrix (i.e. scarring).2,3

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  1. A. J. Rees
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Editors and Affiliations

  1. University of Aberdeen, UK

    Graeme R. D. Catto MD, DSc, FRCP (Lond., Edin. and Glasg.) (Professor of Medicine) (Professor of Medicine)

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Rees, A.J. (1990). Proliferation of Glomerular Cells. In: Catto, G.R.D. (eds) Glomerulonephritis. New Clinical Applications: Nephrology, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2225-9_6

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  • DOI: https://doi.org/10.1007/978-94-009-2225-9_6

  • Publisher Name: Springer, Dordrecht

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