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5-ASA in Ulcerative Colitis

  • Chapter
Inflammatory Bowel Diseases 1990

Part of the book series: Developments in Gastroenterology ((DIGA,volume 11))

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Abstract

5-ASA, the active moiety of sulfasalazine, offers the advantages of “targeted” delivery of a mucosal anti-inflammatory agent with equal or enhanced therapeutic potency and a markedly reduced side-effect profile in IBD. Although the mechanism(s) of action remain uncertain, the compound can be used as a model to study both anti-inflammatory mediators and intestinal delivery systems for alternative non-systemic therapies.

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Authors and Affiliations

  1. Department of Medicine Section of Gastroenterology, University of Chicago Medical Center, 5841 So. Maryland Avenue, Chicago, IL, 60637, USA

    Stephen B. Hanauer M.D.

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  1. Stephen B. Hanauer M.D.
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Editors and Affiliations

  1. Department of Medicine, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel

    D. Rachmilewitz  & J. Zimmerman  & 

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© 1990 Kluwer Academic Publishers

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Hanauer, S.B. (1990). 5-ASA in Ulcerative Colitis. In: Rachmilewitz, D., Zimmerman, J. (eds) Inflammatory Bowel Diseases 1990. Developments in Gastroenterology, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1980-8_20

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  • DOI: https://doi.org/10.1007/978-94-009-1980-8_20

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7385-1

  • Online ISBN: 978-94-009-1980-8

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