Abstract
Some 100 years ago experimental drug research in animals started on an industrial scale and the first drugs were antipyrine and acetylsalicylic acid. Experimental chemotherapy of infectious diseases was started by Paul Ehrlich who was able to standardize an animal model, the tryposoma infection of the mouse, which enabled him to detect finally the first compound active against syphilis which was tolerated by the host (Fig. 1) [1]. Compound number 606 finally was the famous Salvarsan known also as Ehrlich Hata 606.
Dedicated to Prof. Dr. rer. nat. Hansgeorg Gareis on the occasion of his 60th birthday.
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© 1990 Kluwer Academic Publishers, Dordrecht
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Kramer, M. (1990). Animal use in drug research. In: Garattini, S., van Bekkum, D.W. (eds) The Importance of Animal Experimentation for Safety and Biomedical Research. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1904-4_25
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DOI: https://doi.org/10.1007/978-94-009-1904-4_25
Publisher Name: Springer, Dordrecht
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