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Experimental models of aluminum toxicity

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Aluminum and renal failure

Part of the book series: Developments in Nephrology ((DINE,volume 26))

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Abstract

While the clinical ramifications of aluminum toxicity are well known and have recently been well documented, many of the underlying causes for these toxic effects are unknown. In order to understand the bases of these clinically-observed symptoms, experimental systems have been designed and studied which have attempted to approximate some of the effects of aluminum in the human body. These model systems have typically been designed to study the effects of aluminum on skeletal and central nervous system tissues, as well as to investigate aluminum metabolism and turnover. Further, such endeavors may be grouped into two experimental genre: Physical-chemical and biological studies.

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Authors
  1. Norman C. Blumenthal
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  2. John C. Grew
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Editor information

Editors and Affiliations

  1. University of Antwerp, Department of Nephrology-Hypertension, University Hospital Antwerp, Wilrijkstraat 10, B-2520, Edegem, Belgium

    Marc E. de Broe

  2. Nephrology Section (W111L), VA Medical Center West Los Angeles, University of California, Wilshire and Sawtelle Blvds, Los Angeles, CA, 90073, USA

    Jack W. Coburn

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© 1990 Kluwer Academic Publishers

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Blumenthal, N.C., Grew, J.C. (1990). Experimental models of aluminum toxicity. In: de Broe, M.E., Coburn, J.W. (eds) Aluminum and renal failure. Developments in Nephrology, vol 26. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1868-9_13

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  • DOI: https://doi.org/10.1007/978-94-009-1868-9_13

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7333-2

  • Online ISBN: 978-94-009-1868-9

  • eBook Packages: Springer Book Archive

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