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What determines the vigour of the immune response to Helicobacter pylori?

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Book cover Helicobacter pylori

Abstract

The term ‘vigour’ refers to both the ‘active strength’ and the ‘effective force’ of a response. This difference is exemplified by the quandary encountered when studying the immune response to Helicobacter pylori infection. Patients infected with H. pylori mount an antibody response and possibly even a cell-mediated or T cell response; yet the infection persists. This suggests that the vigour of the immune response, that is, strength of the antibody or cell-mediated immunity, is not paralleled by the effectiveness of the immune response, i.e. the ability to either prevent or eliminate the infection. It is in this context that we will consider the factors that contribute to the vigour of the immune response to H. pylori.

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Authors
  1. K. Croitoru
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  2. D. Snider
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Editors and Affiliations

  1. Division of Gastroenterology, McMaster University Medical Centre, 1200 Main Street West, Room 4W8, Hamilton, Ontario, L8N 3Z5, Canada

    Richard H. Hunt (Professor of Medicine, Director) (Professor of Medicine, Director)

  2. Department of Gastroenterology and Hepatology, Academic Medical Centre, 9 Meibergdreef, 1105 AZ, Amsterdam, The Netherlands

    Guido N. J. Tytgat (Professor) (Professor)

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© 1996 Kluwer Academic Publishers and Axcan Pharma

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Croitoru, K., Snider, D. (1996). What determines the vigour of the immune response to Helicobacter pylori?. In: Hunt, R.H., Tytgat, G.N.J. (eds) Helicobacter pylori. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1792-7_16

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  • DOI: https://doi.org/10.1007/978-94-009-1792-7_16

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