Perfluorocarbon Emulsions: One Approach to Intravenous Artificial Respiratory Gas Transport

  • Bruce D. Spiess
Part of the Developments in Critical Care Medicine and Anesthesiology book series (DCCA, volume 31)


The viral infectious risks of allogeneic transfusion have recently been reduced (1). This is due to changes in viral marker testing along with surrogate risk testing using a number of biochemical tests. These data have been widely heralded with comments that the blood supply is now the safest it has ever been. This may be true; however, these data are reported from one study only and a wide range of risks associated with blood transfusion exist that will not be changed by reducing viral transmission. These risks include ABO and Rh incompatibility, graft versus host disease, volume overload, and immunosuppression leading to increased secondary infection or solid tumor recurrence. Therefore, even though viral transmission is less troublesome today than it was 5 years ago, allogeneic blood transfusion carries significant risks. For many years physicians have searched for ways to circumvent those risks. The development of safe, more efficacious, and cost effective oxygen transport medias are being investigated.


Blood Substitute Partial Liquid Ventilation Perfluorocarbon Emulsion Sodium Chloride Potassium Oxygen Carbon Dioxide 
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© Kluwer Academic Publishers 1996

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  • Bruce D. Spiess

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