Primary prevention of triggering of coronary heart disease

  • Ira S. Ockene
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 170)


Joslin was of course describing the circumstances that lead to the clinical expression of diabetes mellitus, but the quotation would be equally appropriate as a summary of the conditions that precede a myocardial infarction or sudden death in an individuals with underlying coronary heart disease (CHD). It is essential that we remember that a “trigger” is not a root cause, but rather is a last straw, a final event that causes a last link in a chain of events to be put in place, and thus results in an abrupt change in clinical status. The event itself is of such a dramatic nature that the conditions immediately preceding it are often mistakenly thought of as causal and necessary, rather than as accelerators of a process likely to have inevitably led to the same outcome, albeit somewhat later.


Coronary Heart Disease Rheumatic Heart Disease Coronary Heart Disease Event Chronic Degenerative Disease French Paradox 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Kluwer Academic Publishers 1996

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  • Ira S. Ockene

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