Abstract
It has been known for a long time that occlusive arterial thrombosis develops almost always in atherosclerotic arteries, practically never in normal vessels, but the mechanism through which atherosclerosis promotes thrombosis remained obscure. In the relatively few cases in which the thrombus developed over a severely ulcerated atheroma, there was no question regarding the pathogenesis of the thrombus, but in most cases the large occlusive thrombi developed over seemingly intact atheroma caps that were overlying hemorrhagic lipid cores [1].
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Constantinides, P. (1996). Some thoughts on the causes of coronary thrombosis in atherosclerotic arteries and the research necessary for their future exploration. In: Willich, S.N., Muller, J.E. (eds) Triggering of Acute Coronary Syndromes. Developments in Cardiovascular Medicine, vol 170. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1577-0_16
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DOI: https://doi.org/10.1007/978-94-009-1577-0_16
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