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Coronary Reserve and Angina Therapy

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Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 81))

Abstract

Several studies have confirmed that patients with vasospastic angina have a variable ischemia threshold for exercise [1–3]. In our group, Molinero has demonstrated [4, 5] that variable ischemia threshold, identified by different serial electrocardiographic effort tests, is frequent (12/20 cases) in patients with angina at rest and with exertion (mixed angina). Servi [1] identified a significant increment in exercise tolerance and regional coronary flow after administration of nifedipine in patients with effort angina and variable electrocardiographic threshold. Parting from these findings, our study had a double objective:

  1. a)

    identification of the vasospastic component of effort angina by evaluating coronary reserve, and

  2. b)

    appraisal of the therapeutic value of identifying this component.

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References

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© 1988 Kluwer Academic Publishers

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Ezkurdia, M.I., Salcedo, J.M.A., Romeo, J.B., de Miguel, E.M., Martinez, J.U. (1988). Coronary Reserve and Angina Therapy. In: de Luna, A.B., Betriu, A., Permanyer, G. (eds) Therapeutics in Cardiology. Developments in Cardiovascular Medicine, vol 81. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1333-2_52

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  • DOI: https://doi.org/10.1007/978-94-009-1333-2_52

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7094-2

  • Online ISBN: 978-94-009-1333-2

  • eBook Packages: Springer Book Archive

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