Anticoagulant Drugs & Surgery

  • G. M. Woerlee
Part of the Developments in Critical Care Medicine and Anesthesiology book series (DCCA, volume 18)


Anticoagulant drugs may be administered to patients coming for surgery for a variety of reasons. The anaesthetist should have a practical working knowledge of the effects of these drugs and the methods of reversing their effects. There are two basic types of anticoagulant drugs in clinical use, the orally administered vitamin-K antagonists, and the heparins.


Elimination Half Life Elimination Kinetic Anticoagulant Drug Plasma Elimination Half Life Intravascular Catheter 
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    Gurewich, V., et al., (1978). Hemostatic Effects of Uniform, Low-Dose Subcutaneous Heparin in Surgical Patients. ARCHIVES OF INTERNAL MEDICINE, 138, 41–44.PubMedCrossRefGoogle Scholar
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    Goodman, L.S. et al., (1985), “Goodman and Gilman’s Pharmacological Basis of Therapeutics”, 7th ed., pub. Macmillan.Google Scholar
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    Cohen, J.A., (1984). Activated coagulation time method for control of heparin is reliable during cardiopulmonary bypass. ANESTHESIOLOGY, 60, 121–124.PubMedCrossRefGoogle Scholar

Copyright information

© Kluwer Academic Publishers 1988

Authors and Affiliations

  • G. M. Woerlee
    • 1
  1. 1.Department of AnaesthesiaUniversity Hospital of LeidenThe Netherlands

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