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Glomerular and associated tubular injury by light chains. The spectrum of damage and effect of treatment

  • Netar P. Mallick
  • G. Williams
Part of the Developments in Nephrology book series (DINE, volume 22)

Abstract

Immunoglobulin light chains are physically and electrically heterogeneous. The distinctive amino-acid sequence of its variable region must account for the solubility, iso-electric point and affinity for other proteins of a given light chain and for its ability or otherwise to form aggregates, or to damage particular aspects of renal tubular metabolism.

Keywords

Light Chain Monoclonal Gammopathy Free Light Chain Membranoproliferative Glomerulonephritis Kappa Light Chain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers, Dordrecht 1988

Authors and Affiliations

  • Netar P. Mallick
    • 1
  • G. Williams
  1. 1.Department of Renal MedicineCentral Manchester Health Authority, Manchester Royal InfirmaryManchesterUK

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