Abstract
There is evidence to support the possibility that in the intact heart muscle fibre stress and extent of shortening are homogeneous. If this is assumed to be true, a model of the left ventricle can be constructed where these properties are achieved by appropriate orientation of fibres and torsional movement of the ventricle as a whole. The original cylindrical model was developed into one which was independent of ventricular shape. The equation:
Plv = Sf/3 ln(1+Vw/Viv)
(where Plv = left ventricular pressure, Sf = fibre stress, Vw = left ventricular wall volume and Viv = left ventricular cavity volume) gives the relationship of muscle force to ventricular pressure. The equation:
Ls/LSo = [(1+x)1 + x/xx]1/3
(where x = Vlv/Vw, Ls = sarcomere length and Lso = extrapolated sarcomere length at zero cavity volume) gives the relationship of sarcomere length to ventricular cavity and wall size. The model is equally applicable to mice and elephants and gives realistic ventricular haemodynamic and muscle mechanical values. It can also accommodate the right ventricle, valves, chordae tendinae and papillary muscles.
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© 1988 Kluwer Academic Publishers
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Arts, T., Reneman, R.S. (1988). The Importance of the Geometry of the Heart to the Pump. In: ter Keurs, H.E.D.J., Noble, M.I.M. (eds) Starling’s Law of The Heart Revisited. Developments in Cardiovascular Medicine, vol 89. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1313-4_8
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DOI: https://doi.org/10.1007/978-94-009-1313-4_8
Publisher Name: Springer, Dordrecht
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