Echographical follow-up of choroidal melanoma after irradiation with Iodine 125

  • A. Stanowsky
  • I. Kreissig
Part of the Documenta Ophthalmologica Proceedings Series book series (DOPS, volume 51)


Nine patients with malignant choroidal melanomas treated with radioactive Iodine 125 have been followed up since 1984 with the B-scan and the standardized A-scan procedures. Within the first month after beginning of treatment the echograms showed differences among the tumours in prominence, structure and inner reflectivity.

In contrast to this all tumours showed an increase in vascularisation. This became particularly clear with video-echography.

Later on an increase of reflectivity and an inhomogeneity of the inner structure were predominant, as is the case with other radiation procedures. Tumour prominence decreased in all patients.

Our impression is that the echographically determined degree to which vascularisation increases after irradiation is an indicator of the therapy’s effectiveness.


Cent Degree Base Diameter Radioactive Iodine Choroidal Melanoma Radiation Procedure 
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  1. Coleman DJ, Lizzi FL, Jack RL. 1977. Ultrasonography of the eye and orbit. Philadelphia: Lea & Febiger.Google Scholar
  2. Hasenfratz, G. 1985. Echographische Befunde bei Aderhaut-Melanoblastomen nach Ruthenium-Therapie. Fortschr Ophthalmol 82: 453–456.PubMedGoogle Scholar
  3. Lommatzsch PK. 1979. Radiotherapie der intraocularen Tumoren, insbesondere bei Aderhautmelanomen. Klin Mbl Augenheilk 174: 948–958.PubMedGoogle Scholar
  4. Lüllwitz W, Hallermann D, Schröder W. 1979. Zum klinischen Verlauf des malignen Melanoms der Aderhaut nach Strahlentherapie mit Rul06/Rh106 — Applikator. Ber Dtsch Ophthalmol Ges 76:181–183.Google Scholar
  5. Ossoinig C. 1979. Standardized echography: basic principles, clinical applications and results. In: RL Dallow (ed) Ophthalmic ultrasonography: comparative techniques. (Int Ophthalmol Clin 19/4), Little, Brown & Co., Boston.Google Scholar
  6. Packer S, Rotman M, Salanitro P. 1984. Iodine-125 irradiation of choroidal melanoma. Ophthalmology 91:1700–1708.PubMedGoogle Scholar
  7. Stallard HB. 1960. Malignant melanoma of the choroid treated with radioactive applicators. Trans Ophthalmol Soc U.K. 79: 373–392.Google Scholar

Copyright information

© Kluwer Academic Publisher 1988

Authors and Affiliations

  • A. Stanowsky
    • 1
    • 2
  • I. Kreissig
    • 1
  1. 1.Ophthalmology III: Diseases of the Posterior EyeUniversity Eye Clinic TübingenTübingenGermany
  2. 2.Zentralklinikum AugsburgAugsburgGermany

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