Immune reactions in the rheumatoid synovial tissue

  • L. Klareskog
  • H. Wigzell


For the understanding of the immunopathogenic process in the rheumatoid synovial tissue, there are two issues that are of particular interest: (i) which regulatory and effector mechanisms are involved in the formation of the rheumatic lesions and, most importantly, (ii) what is the specificity (specificities) of the immune reactions responsible for the subsequent development of the multiple immunological and inflammatory events that can be observed in the joints of individuals with advanced rheumatoid arthritis (RA).


Rheumatoid Arthritis Rheumatoid Factor Synovial Tissue Synovial Cell Juvenile Rheumatoid Arthritis 
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© MTP Press Limited 1988

Authors and Affiliations

  • L. Klareskog
  • H. Wigzell

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