The skin as a chemical barrier
The skin is an incomplete barrier, water (and some gases) passing through it to some extent. It is also vulnerable to chemical attack.
This barrier property of skin has important therapeutic, toxico-logical and dermatological consequences1. In this paper, I shall concentrate solely on the skin as a chemical barrier in respect to irritants and potential sensitizers.
KeywordsStratum Corneum Barrier Function Irritant Contact Dermatitis Chemical Barrier Skin Surface Lipid
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- 1.Barry, B.W. (1983). Dermatological Formulations: Percutaneous Absorption. (New York: Marcel Dekker Inc.)Google Scholar