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Mast Cells, Mediators and Disease pp 241–258Cite as

Target Tissues for Mediators in Human Allergic Reactions

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Part of the book series: Immunology and Medicine Series ((IMME,volume 7))

Abstract

Inflammation is a fundamental component of the body’s response to trauma and the invasion of foreign material. Although inflammation can occur in all tissues, as the structure of tissue at various sites differs, the response of the tissues are not necessarily the same. It is the purpose of this chapter to review the spectrum of mediators released during human allergic reactions in general, and in three specific target sites for the reaction, i.e. the skin, nose and airway. The effect of the mediators on the target tissues and the evidence for the relative importance for each mediator, or group of mediators, in the production of the reaction at each specific site is also discussed.

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  1. R. W. Fuller
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Editors and Affiliations

  1. Immunopharmacology Group, Clinical Pharmacology, University of Southampton, Southampton, SO9 4XY, UK

    S. T. Holgate (MRC Clinical Reasearch Professor of Immunopharmacology) (MRC Clinical Reasearch Professor of Immunopharmacology)

  2. Faculty of Medicine, Level D, Centre Block, Southampton General Hospital, Southampton, SO9 4XY, UK

    S. T. Holgate (MRC Clinical Reasearch Professor of Immunopharmacology) (MRC Clinical Reasearch Professor of Immunopharmacology)

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© 1988 Kluwer Academic Publishers

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Fuller, R.W. (1988). Target Tissues for Mediators in Human Allergic Reactions. In: Holgate, S.T. (eds) Mast Cells, Mediators and Disease. Immunology and Medicine Series, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1287-8_9

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  • DOI: https://doi.org/10.1007/978-94-009-1287-8_9

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7072-0

  • Online ISBN: 978-94-009-1287-8

  • eBook Packages: Springer Book Archive

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