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Antimicrobial Functions of Neutrophils

  • Chapter
Phagocytes and Disease

Part of the book series: Immunology And Medicine Series ((IMME,volume 11))

Abstract

Once bacteria invade the tissues, the outcome of the host-parasite relationship is determined by the interaction of bacterial virulence factors on the one hand and the bacteriolytic activity of serum and the phagocytic capacity of polymorphonuclear (PMN) and mononuclear leukocytes (MN) on the other1-10. Exposure of some bacteria (especially Gram-negative bacteria such as Neisseria spp. and some of the Enterobacteriaceae) to normal human serum results in a loss of viability and sometimes in their dissolution11. This may play an important role in protecting the host against infections by endogenous and exogenous bacteria.

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Authors
  1. M. Rozenberg-Arska
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  2. I. M. Hoepelman
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  3. J. Verhoef
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Editors and Affiliations

  1. New England Medical Center Hospitals, Tufts University School of Medicine, Boston, Massachusetts, USA

    M. S. Klempner , B. Styrt  & J. Ho ,  & 

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© 1989 Kluwer Academic Publishers

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Rozenberg-Arska, M., Hoepelman, I.M., Verhoef, J. (1989). Antimicrobial Functions of Neutrophils. In: Klempner, M.S., Styrt, B., Ho, J. (eds) Phagocytes and Disease. Immunology And Medicine Series, vol 11. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1279-3_3

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  • DOI: https://doi.org/10.1007/978-94-009-1279-3_3

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7068-3

  • Online ISBN: 978-94-009-1279-3

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