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Fat Malabsorption, Vitamin E Deficiency, Scoliosis and Cataracts

  • R. D. Griffiths
  • C. J. Taylor
  • D. M. Isherwood
  • M. J. Jackson

Abstract

The neurological sequelae of vitamin E deficiency occurring as a result of steatorrhoea, specific defects in fat absorption (abetalipoproteinaemia), and in a selective defect of vitamin E absorption (Harding et al., 1985) are now well described (Muller et al., 1983). The importance of assessing vitamin E status is illustrated in this report on the presentation, treatment and progress of an atypical case of hypolipoproteinaemia associated with cataracts and scoliosis.

Keywords

Coeliac Disease Jejunal Biopsy Plasma Creatine Kinase Activity Spinocerebellar Degeneration Selective Defect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Harding, A. E., Matthews, S., Jones, S., Ellis, C. J. K., Booth, I. W. and Muller, D. P. R. Spinocerebellar degeneration associated with a selective defect of vitamin E absorption. N. Engl J. Med. 313 (1985) 32–35PubMedCrossRefGoogle Scholar
  2. Muller, D. P. R., Lloyd, J. K. and Wolff, O. H. Vitamin E and neurological function. Lancet 1 (1983) 225–228PubMedCrossRefGoogle Scholar
  3. Traber, M. G., Sokol, R. J., Ringel, S. P., Neville, H. E., Thellman, C. A., and Kayden, H. J. Lack of tocopherol in peripheral nerves of vitamin E-deficient patients with peripheral neuropathy. N. Engl. J. Med. 317 (1987) 262–265PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1988

Authors and Affiliations

  • R. D. Griffiths
    • 1
  • C. J. Taylor
    • 2
  • D. M. Isherwood
    • 3
  • M. J. Jackson
    • 1
  1. 1.Department of MedicineUniversity of LiverpoolUK
  2. 2.Department of PaediatricsUniversity of SheffieldUK
  3. 3.Department of Chemical PathologyRoyal Liverpool Childrens HospitalAlder HeyUK

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