Maternal Immune Responses to the Fetus in Human Pregnancy

  • I. L. Sargent
  • C. W. G. Redman
Part of the Immunology and Medicine Series book series (IMME, volume 10)


The fetus expresses paternally derived antigens that are genetically foreign to the mother, so how does the fetal allograft survive gestation, unharmed by the maternal immune system1? In fact, the fetus has no direct contact with the maternal immune system, and it is the trophoblast of the placenta and fetal membranes which forms the interface between maternal and fetal tissues. This chapter examines the nature of maternal immune responses to the fetoplacental unit and how they are regulated.


Natural Killer Cell Suppressor Cell Mixed Lymphocyte Reaction Major Histocompatibility Gene Complex Human Pregnancy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Kluwer Academic Publishers 1989

Authors and Affiliations

  • I. L. Sargent
  • C. W. G. Redman

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