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Bacteria and gastroduodenal inflammation

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Advances in Peptic Ulcer Pathogenesis

Abstract

The stomach and upper gut are normally sterile with only transient flora appearing following ingestion of food. The gastric defences including acid, mucus, lysozyme and immunoglobulins protect the upper gut from bacterial colonization. With decreasing gastric acidity, which occurs normally with ageing and with conditions such as pernicious anaemia and following gastric surgery, the stomach may become colonized with faecal as well as oral bacteria1. Patients with hypochlorhydria are also more susceptible to enteric infections such as cholera and salmonellosis2.

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Authors
  1. B. J. Rathbone
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  2. J. I. Wyatt
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  3. R. V. Heatley
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Editor information

Editors and Affiliations

  1. Department of Gastroenterology, Hope Hospital, Salford, Lancs, UK

    W. D. W. Rees MD, MRCP (Consultant Physician and Gastroenterologist) (Consultant Physician and Gastroenterologist)

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© 1988 MTP Press Limited

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Rathbone, B.J., Wyatt, J.I., Heatley, R.V. (1988). Bacteria and gastroduodenal inflammation. In: Rees, W.D.W. (eds) Advances in Peptic Ulcer Pathogenesis. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1245-8_5

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  • DOI: https://doi.org/10.1007/978-94-009-1245-8_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7052-2

  • Online ISBN: 978-94-009-1245-8

  • eBook Packages: Springer Book Archive

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