Epidemiology of peptic ulcer disease

  • A. Sonnenberg
  • A. Sengupta
  • P. Bauerfeind

Abstract

The epidemiology of both gastric and duodenal ulcer is characterized by marked geographic and temporal variations. The incidence, prevalence and mortality of gastric and duodenal ulcer vary four- to ten-fold among different European countries1. During the past 20–30 years the number of patients who died from peptic ulcer disease2-5, who have been operated upon5, 6, who saw physicians7, 8 or were hospitalized for peptic ulcer disease9-11 have decreased by more than 100 per cent. These changes occurred within so short a period that a genetic basis can be ruled out. Thus, it seems likely that they stem from changes in environmental risk factors. The geographic variability of ulcer prevalence among populations of similar ethnicity and comparable medical standards also hints at environmental influences. Judging from their effect, it appears that environmental factors are of sufficient magnitude to constitute a fertile ground for inquiry because such information would engender the development of potent measures for prevention and treatment of gastric and duodenal ulcer disease. In addition, knowledge of environmental risk factors could provide new insights and methods to study the pathophysiology of peptic ulcer.

Keywords

Peptic Ulcer Duodenal Ulcer Peptic Ulcer Disease Disability Pension Salt Consumption 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© MTP Press Limited 1988

Authors and Affiliations

  • A. Sonnenberg
  • A. Sengupta
  • P. Bauerfeind

There are no affiliations available

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