Abstract
The evolution of living organisms is caused primarily by mutations that may subsequently be eliminated or become fixed in the genome. While it is generally agreed that elimination affects deleterious mutations and occurs by negative selection, fixation has been visualized as due either (i) to positive Darwinian selection acting on advantageous mutations or (ii) to random genetic drift acting on selectively neutral (i. e. selectively equivalent) mutations. Since both advantageous and neutral mutations definitely can be fixed in evolution, the issue is of a quantitative and not of a qualitative nature and concerns the predominance of deterministic or stochastic events in genome evolution. That the issue is a difficult one is proved by the fact that this debate has gone on, in the form just stated, for almost twenty years.
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© 1989 Kluwer Academic Publishers, Dordrecht, The Netherlands.
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Bernardi, G., Bernardi, G. (1989). Randomness and Natural Selection in Genome Evolution. In: Maruani, J. (eds) Molecules in Physics, Chemistry, and Biology. Topics in Molecular Organization and Engineering, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1173-4_1
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DOI: https://doi.org/10.1007/978-94-009-1173-4_1
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