Computer Controlled System for On-line Monitoring of a Fermentation Process

  • J. Nielsen
  • K. Nikolajsen
  • J. Villadsen

Summary

A computer controlled laboratory system is set up in order to study lactic acid fermentation kinetics using Streptococcus cremoris. The system consists of a laboratory fermentor with on-line Flow Injection Analysers for glucose, lactic acid, protein and optical density. Sample withdrawal and operation of the analytical system is controlled by a PC, which also performs data acquisition, calibration and calculation. The layout of the system is shown in Figure 1. The system is well suited for studies of lactic acid fermentation at dynamic as well as at steady-state conditions. The overall goal of the investigation is to set up a simple structured mathematical model that describes growth and product formation during both steady-state and dynamic conditions.

Keywords

Lactic Acid Flow Injection Analysis Gluconic Acid Lactic Acid Concentration Lactic Acid Fermentation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Nikolajsen, K., J. Nielsen and J. Villadsen “In-line Flow Injection Analysis for Monitoring Lactic Acid Fermentations”. Anal. Chim. Acta 214 (1988) p. 137–145.CrossRefGoogle Scholar
  2. Nielsen, J., K.Nikolajsen and J. Villadsen “FIA for On-line Monitoring of Important Lactic Acid Fermentation Variables”. Accepted for publication in Biotechnol. Bioeng. (1988).Google Scholar
  3. Ridder, C, E.H.Hansen and J. Ruzicka “Flow Injection Analysis of Glucose in Human Serum by Chemluminiscence”. Anal. Lett. 15 (1982) p. 1751–1766.Google Scholar
  4. Ruzicka, J. and E.H.Hansen “Flow Injection Analysis” 2.ed. (1988) John Wiley & Sons Inc.Google Scholar

Copyright information

© Society of Chemical Industry 1989

Authors and Affiliations

  • J. Nielsen
    • 1
  • K. Nikolajsen
    • 1
  • J. Villadsen
    • 1
  1. 1.Department of BiotechnologyThe Technical University of DenmarkLyngbyDenmark

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