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Measurement of Biological Reaction Rates Using Advanced pH Control Systems

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Computer Applications in Fermentation Technology: Modelling and Control of Biotechnological Processes

Abstract

This paper shows that the advanced pH control systems proposed here can be widely applied to measurement of biological reaction rates. In many cases, biological reaction rate could be calculated from the amount of base or acid required for keeping pH constant. A microbial growth rate and an enzyme reaction rate have been estimated successfully using the advanced pH control system, such as the disturbance predictive controller and the PF systems with learning mechanism. The basic analysis also showed that the overall production rate of acid in a batch culture of hybridoma cell must be estimated using the advanced pH control system.

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References

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Author information

Authors and Affiliations

  1. Department of Fermentation Technology, Osaka University, Suita, Osaka, 565, Japan

    Suteaki Shioya

Authors
  1. Suteaki Shioya
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Editor information

Editors and Affiliations

  1. SERC Centre for Biochemical Engineering, University College London, UK

    N. M. Fish

  2. RHM Research Ltd, High Wycombe, UK

    R. I. Fox

  3. Department of Electronic and Electrical Engineering, University College London, UK

    N. F. Thornhill

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© 1989 Society of Chemical Industry

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Shioya, S. (1989). Measurement of Biological Reaction Rates Using Advanced pH Control Systems. In: Fish, N.M., Fox, R.I., Thornhill, N.F. (eds) Computer Applications in Fermentation Technology: Modelling and Control of Biotechnological Processes. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1141-3_3

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  • DOI: https://doi.org/10.1007/978-94-009-1141-3_3

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7006-5

  • Online ISBN: 978-94-009-1141-3

  • eBook Packages: Springer Book Archive

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