Hydrodynamic and Kinetic Modelling of a Flocculating Bioreactor with Cell Recycle

  • J. A. Teixeira
  • M. Mota
  • S. Feyo de Azevedo


Research and development in advanced technology for fermentation processes is currently foccused in obtaining high density cell cultures. From the main techniques currently employed, flocculation is the one with the lowest operating costs (less mixing and recirculation energy). This is a relevant incentive for the study of its suitability for the production of medium or low added value products. This work deals with the production of ethanol from lactose, using a flocculating strain of Kluyveromyces marxianus in a flocculation bioreactor with cell recycle.


Aeration Rate Plug Flow Reactor Continuous Stir Tank Reactor Kluyveromyces Marxianus Lactose Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Uribelarrea J.L., Pacaud S., Goma G., “Biotechnol. Letters”;, 7 (2), 75 (1985).CrossRefGoogle Scholar
  2. 2.
    Atkinson B., “Biochemical Reactors”, Pion Limited, Londres (1974).Google Scholar
  3. 3.
    Teixeira J.A., Mota M., in “Bioenergy European Research and Development”, Contractors’ Catalogue, Brussels (1987).Google Scholar
  4. 4.
    Kreger van Rij N.J.W., “The Yeasts—a taxonomic study”, Elsevier Ed., (1984).Google Scholar
  5. 5.
    Costa M., in “Análise de Hidratos do Carbono”, Coimbra (1984).Google Scholar
  6. 6.
    Meyer R.R., Roth P.M., J. Ins. Maths Applies., 9, 218 (1976).CrossRefGoogle Scholar
  7. 7.
    Feyo de Azevedo S., Salcedo R., Gonçalves M.J., in “Recent Progrès in Génie des Procédés”, Vol 2, no 6, ed. S. Domenech, X. Joulia, B. Kochret, 199–203, Lavoisier Techniques, Paris (1988).Google Scholar
  8. 8.
    Lapidus L., Seinfeld J.H., “Numerical Solutions of Ordinary Differential Equations”, Academic Press, N.Y. (1971).Google Scholar
  9. 9.
    Bailey J. E., Ollis D. F., “Biochemical Engineerig Fundamentals”, Mc Graw-Hill Book Company, N.Y. (1977).Google Scholar
  10. 10.
    Alba S., Shoda M., Nagatani M.“Biotech. Bioeng.”, 10,845 (1968). CrossRefGoogle Scholar

Copyright information

© Society of Chemical Industry 1989

Authors and Affiliations

  • J. A. Teixeira
    • 1
  • M. Mota
    • 1
  • S. Feyo de Azevedo
    • 1
  1. 1.Centro de Engenharia Quimica da Universidade do PortoFaculdade de EngenhariaPorto CodexPortugal

Personalised recommendations